Evidence map›Paper›PMID 32641060›Full record

ArticleEnvironmental health : a global access science source2020

Intracranial tumors of the central nervous system and air pollution - a nationwide case-control study from Denmark.

Aslak Harbo Poulsen, Ulla Arthur Hvidtfeldt, Mette Sørensen, Robin Puett, Matthias Ketzel, Jørgen Brandt, Camilla Geels, Jesper H Christensen, Ole Raaschou-Nielsen

Open access · goldAbstract read
In one paragraph

Article in Environmental health : a global access science source, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Impact of Pollution on Cancer: A Systematic Review and Meta-Analysis with Focus on Air Pollution.International journal of environmental research and public health · 2026
    Pooled it
  2. Environmental Hazards and Glial Brain Tumors: Association or Causation?International journal of molecular sciences · 2025
    Review
  3. Review
  4. Article
  5. Article
  6. Impacts of Environmental Pollution on Brain Tumorigenesis.International journal of molecular sciences · 2023
    Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Aslak Harbo PoulsenDanish Cancer Society Research Center, Strandboulevarden 49, DK-2100, Copenhagen Ø, Denmark. Aslak@Cancer.DK.ORCID 0000-0003-4456-4169
Ulla Arthur HvidtfeldtDanish Cancer Society Research Center, Strandboulevarden 49, DK-2100, Copenhagen Ø, Denmark.
Mette SørensenDanish Cancer Society Research Center, Strandboulevarden 49, DK-2100, Copenhagen Ø, Denmark.
Robin PuettDanish Cancer Society Research Center, Strandboulevarden 49, DK-2100, Copenhagen Ø, Denmark.
Matthias KetzelDepartment of Environmental Science, Aarhus University, Roskilde, Denmark.
Jørgen BrandtDepartment of Environmental Science, Aarhus University, Roskilde, Denmark.
Camilla GeelsDepartment of Environmental Science, Aarhus University, Roskilde, Denmark.
Jesper H ChristensenDepartment of Environmental Science, Aarhus University, Roskilde, Denmark.
Ole Raaschou-NielsenDanish Cancer Society Research Center, Strandboulevarden 49, DK-2100, Copenhagen Ø, Denmark.
Aarhus University · DKDanish Cancer Society · DKRoskilde University · DK

Funding

Nordisk Ministerråd 75007
6 · The paper itself

Abstract

backgroundInconclusive evidence has suggested a possible link between air pollution and central nervous system (CNS) tumors. We investigated a range of air pollutants in relation to types of CNS tumors.

methodsWe identified all (n = 21,057) intracranial tumors in brain, meninges and cranial nerves diagnosed in Denmark between 1989 and 2014 and matched controls on age, sex and year of birth. We established personal 10-year mean residential outdoor exposure to particulate matter < 2.5 μm (PM

resultsMalignant tumors of the intracranial CNS was associated with BC (OR: 1.034, 95%CI: 1.005-1.065 per IQR. For NO

conclusionOur results suggest that air pollution is associated with malignant intracranial CNS tumors and malignant non-glioma of the brain. However, additional studies are needed.

Indexed as

AdultAgedAged, 80 and overAir PollutantsAir PollutionBrain NeoplasmsCase-Control StudiesDenmarkEnvironmental ExposureFemaleHumansIncidenceMaleMiddle AgedNitrous OxideOzoneAir PollutantsNitrous OxideOzoneParticulate MatterSootAir pollutionCNS-tumorsEpidemiologyRegister study

Identifiers

PMID32641060
PMCPMC7346389
OpenAlexW3040878369

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.