ArticleGenetics, selection, evolution : GSE2020
Inbreeding depression for kit survival at birth in a rabbit population under long-term selection.
Article in Genetics, selection, evolution : GSE, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 11 citations in OpenAlex.
- Quantifying genetic load through joint modelling of inbreeding depression and inbreeding load for litter size in rabbits.Genetics, selection, evolution : GSE · 2026Article
- Pedigree-based evaluation of classical, ancestral, and new inbreeding coefficients in Carora and Criollo Limonero dairy cattle populations.Veterinary world · 2026Article
- Whole-genome sequencing reveals patterns of runs of homozygosity underlying genetic diversity and selection in domestic rabbits.BMC genomics · 2025Article
- Pedigree-Based Description of Danubia Alba Rabbit Breed Lines.Animals : an open access journal from MDPI · 2024Article
- Ballou's Ancestral Inbreeding Coefficient: Formulation and New Estimate with Higher Reliability.Animals : an open access journal from MDPI · 2024Article
- Characterizing and Eliminating the Inbreeding Load.Veterinary sciences · 2023Review
- Association of inbreeding and regional equine leucocyte antigen homozygosity with the prevalence of insect bite hypersensitivity in Old Kladruber horse.Animal genetics · 2021Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
Abstract
backgroundAccumulation of detrimental mutations in small populations leads to inbreeding depression of fitness traits and a higher frequency of genetic defects, thus increasing risk of extinction. Our objective was to quantify the magnitude of inbreeding depression for survival at birth, in a closed rabbit population under long-term selection.
methodsWe used an information theory-based approach and multi-model inference to estimate inbreeding depression and its purging with respect to the trait 'kit survival at birth' over a 25-year period in a closed population of Pannon White rabbits, by analysing 22,718 kindling records. Generalised linear mixed models based on the logit link function were applied, which take polygenic random effects into account.
resultsOur results indicated that inbreeding depression occurred during the period 1992-1997, based on significant estimates of the z-standardised classical inbreeding coefficient z.F
conclusionsOur results support the existence of inbreeding depression and its purging with respect to kit survival at birth in this Pannon White rabbit population. However, we were unable to exclude possible confounding from the effects of parity and potentially other environmental factors during the study period, thus our results need to be extended and confirmed in other populations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.