Evidence map›Paper›PMID 32640680›Full record

ArticleJournal of clinical medicine2020

Effect of Vedolizumab on Anemia of Chronic Disease in Patients with Inflammatory Bowel Diseases.

Patrizio Scarozza, Elena De Cristofaro, Ludovica Scucchi, Irene Rocchetti, Irene Marafini, Benedetto Neri, Silvia Salvatori, Livia Biancone, Emma Calabrese, Giovanni Monteleone

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Patrizio ScarozzaDepartment of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
Elena De CristofaroDepartment of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
Ludovica ScucchiDepartment of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
Irene RocchettiStatistical Office, Superior Council of Judiciary, 00185 Rome, Italy.
Irene MarafiniDepartment of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
Benedetto NeriDepartment of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
Silvia SalvatoriDepartment of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
Livia BianconeDepartment of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
Emma CalabreseDepartment of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
Giovanni MonteleoneDepartment of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
University of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnemia of Chronic Disease (ACD) can negatively influence the clinical course of Inflammatory Bowel Disease (IBD) patients. The aim of this study was to evaluate the effect of Vedolizumab on ACD in IBD.

methodsClinical data of 75 IBD patients (25 Crohn's disease (CD) and 50 Ulcerative Colitis (UC)) receiving Vedolizumab in a tertiary referral IBD center were retrospectively evaluated and the effect of the drug on ACD was ascertained at weeks 14 and 24.

resultsACD was diagnosed in 35 (11 CD and 24 UC) out of 75 (47%) IBD patients. At both week 14 and week 24, improvements and resolutions of ACD were achieved by 13/35 (37%) and 11/35 (31%) patients, respectively. Baseline demographic/clinical characteristics did not differ between patients with ACD improvements/resolutions and those with persistent ACD. Clinical response occurred more frequently in patients who achieved ACD resolution (10/11, 91%) than in those without ACD improvement (5/11, 45%,

conclusionsACD occurs in half of the IBD patients and, in nearly two thirds of them, Vedolizumab treatment associates with ACD resolution/improvement.

Indexed as

anemiabiologicsCrohn’s diseaseulcerative colitis

Identifiers

PMID32640680
PMCPMC7408734
OpenAlexW3040472704

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.