Evidence map›Paper›PMID 32640650›Full record

ArticleInternational journal of molecular sciences2020

Investigating REPAIRv2 as a Tool to Edit

Raffaella Melfi, Patrizia Cancemi, Roberta Chiavetta, Viviana Barra, Laura Lentini, Aldo Di Leonardo

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Molecular Approaches Fighting Nonsense.International journal of molecular sciences · 2021
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Raffaella MelfiDepartment of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, 90128 Palermo, Italy.ORCID 0000-0003-4463-8156
Patrizia CancemiDepartment of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, 90128 Palermo, Italy.ORCID 0000-0002-3951-7213
Roberta ChiavettaDepartment of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, 90128 Palermo, Italy.
Viviana BarraDepartment of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, 90128 Palermo, Italy.ORCID 0000-0002-7186-4485
Laura LentiniDepartment of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, 90128 Palermo, Italy.
Aldo Di LeonardoDepartment of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, 90128 Palermo, Italy.ORCID 0000-0003-4760-7179
University of Palermo · IT

Funding

Fondazione per la Ricerca sulla Fibrosi Cistica FFC#5/2018 to ADLUniversity of Palermo FFR2018 to RMUniversity of Palermo FFR-D15-005543
6 · The paper itself

Abstract

Cystic fibrosis (CF) is caused by mutations in the gene encoding the transmembrane conductance regulator (CFTR) protein. Some CF patients are compound heterozygous or homozygous for nonsense mutations in the

Indexed as

CRISPR-Cas SystemsMutationCell LineCodon, NonsenseCystic FibrosisCystic Fibrosis Transmembrane Conductance RegulatorGene EditingHumansRNA, MessengerCFTR protein, humanCodon, NonsenseCystic Fibrosis Transmembrane Conductance RegulatorRNA, MessengerCRISPR/dCas13bcystic fibrosispremature termination codons (PTCs)RNA editing

Identifiers

PMID32640650
PMCPMC7369808
OpenAlexW3038714273

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.