ArticleNature2020
Structures of fungal and plant acetohydroxyacid synthases.
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Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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32citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
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Who cites it
32 citing papers in PubMed, 70 citations in OpenAlex.
- Synthesis, Herbicidal Activity Evaluation, and Molecular Docking of Novel Acylthioureas as AHAS Inhibitors.Molecules (Basel, Switzerland) · 2026Article
- Design and evolution of the tetracycline repressor into sulfonylurea herbicide-responsive gene switches for field crops.Nature communications · 2026Article
- Development ofBiotechnology reports (Amsterdam, Netherlands) · 2026Article
- Synthesis and Herbicidal Activity of NovelMolecules (Basel, Switzerland) · 2026Article
- Banana aroma is a result of acetohydroxyacid synthase and isopropylmalate synthase alternative isoforms that bypass feedback inhibition.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- De Novo Design and Synthesis of Novel Benzoxazinone Derivatives Targeting Dihydroxyacid Dehydratase.Plant biotechnology journal · 2026Article
- Ectomycorrhizal fungi recruit hyphae-associated bacteria that metabolize thiamine to promote pine symbiosis.The ISME journal · 2026Article
- AHAS structural changes caused by mutations result in differences in binding affinity and resistance to two herbicides inFrontiers in plant science · 2026Article
- Modeling the Mutational Effects on Biochemical Phenotypes of SARS-CoV-2 Using Molecular Fields.Biomolecules · 2025Article
- Structural insights into two thiamine diphosphate-dependent enzymes and their synthetic applications in carbon-carbon linkage reactions.Nature chemistry · 2025Article
- Substrate-based discovery of α-hydroxycarboxylic acid derivatives as potential herbicides targeting dihydroxyacid dehydratase.Nature communications · 2025Article
- Discovery, Herbicidal Activity and Biosynthesis of a Novel Natural Tetramic Acid from Alternaria Species.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- NHC-Mediated Radical Acylation Catalyzed by Thiamine- and Flavin-Dependent Enzymes.Journal of the American Chemical Society · 2025Article
- Breeding of yeast strains with intracellular amino acid accumulation for value-added alcoholic beverages.FEMS yeast research · 2025Review
- An easy and sensitive assay for acetohydroxyacid synthases based on the simultaneous detection of substrates and products in a single step.Analytical and bioanalytical chemistry · 2024Article
- Comparative genome-wide analysis of circular RNAs in Brassica napus L.: target-site versus non-target-site resistance to herbicide stress.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- The ilv2 gene, encoding acetolactate synthase for branched chain amino acid biosynthesis, is required for plant pathogenicity by Leptosphaeria maculans.Molecular biology reports · 2024Article
- Discovery of a New Class of Lipophilic Pyrimidine-Biphenyl Herbicides Using an Integrated Experimental-Computational Approach.Molecules (Basel, Switzerland) · 2024Article
- Article
- Toxicity of herbicides to the marine microalgae Tisochrysis lutea and Tetraselmis sp.Scientific reports · 2024Article
Corrections and comments
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Authors and funding
15 authors at 5 institutions in 3 countries.
Thierry Lonhienne *School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland, Australia. t.lonhienne@uq.edu.au.ORCID http://orcid.org/0000-0001-8788-2840
Yu Shang Low *School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland, Australia.
Mario D GarciaSchool of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland, Australia.ORCID http://orcid.org/0000-0001-8378-7475
Tristan CrollCambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.
Yan GaoShanghai Institute for Advanced Immunochemical Studies, School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
Quan WangShanghai Institute for Advanced Immunochemical Studies, School of Life Science and Technology, ShanghaiTech University, Shanghai, China.ORCID http://orcid.org/0000-0001-5148-5210
Lou BrillaultCentre for Microscopy and Microanalysis, The University of Queensland, Brisbane, Queensland, Australia.
Craig M WilliamsSchool of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland, Australia.
James A FraserSchool of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland, Australia.
Ross P McGearySchool of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland, Australia.
Nicholas P WestSchool of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland, Australia.
Michael J LandsbergSchool of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland, Australia.ORCID http://orcid.org/0000-0002-2464-990X
Zihe RaoShanghai Institute for Advanced Immunochemical Studies, School of Life Science and Technology, ShanghaiTech University, Shanghai, China.ORCID http://orcid.org/0000-0001-9866-2384
Gerhard SchenkSchool of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland, Australia.ORCID http://orcid.org/0000-0001-8619-0631
Luke W GuddatSchool of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland, Australia. luke.guddat@uq.edu.au.ORCID http://orcid.org/0000-0002-8204-8408
The University of Queensland · AUShanghaiTech University · CNNankai University · CNQueensland University of Technology · AUUniversity of Cambridge · GB
Funding
Wellcome Trust 209407/Z/17/Z
Abstract
Acetohydroxyacid synthase (AHAS), also known as acetolactate synthase, is a flavin adenine dinucleotide-, thiamine diphosphate- and magnesium-dependent enzyme that catalyses the first step in the biosynthesis of branched-chain amino acids
Indexed as
Acetolactate SynthaseAdenosine TriphosphateAmino Acids, Branched-ChainArabidopsisCatalytic DomainEnzyme ActivationEvolution, MolecularFeedback, PhysiologicalModels, MolecularMultiprotein ComplexesMycobacterium tuberculosisProtein BindingProtein ConformationProtein SubunitsSaccharomyces cerevisiaeValineAcetolactate SynthaseAdenosine TriphosphateAmino Acids, Branched-ChainMultiprotein ComplexesProtein SubunitsValine
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.