Evidence map›Paper›PMID 32640435›Full record

ArticlePhysics in medicine and biology2020

Automatic multi-needle localization in ultrasound images using large margin mask RCNN for ultrasound-guided prostate brachytherapy.

Yupei Zhang, Zhen Tian, Yang Lei, Tonghe Wang, Pretesh Patel, Ashesh B Jani, Walter J Curran, Tian Liu, Xiaofeng Yang

Open access · greenAbstract read
In one paragraph

Article in Physics in medicine and biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
  2. Review
  3. Systematic review of artificial intelligence in brachytherapy.Journal of contemporary brachytherapy · 2026
    Review
  4. Article
  5. Article
  6. A review of artificial intelligence in brachytherapy.Journal of applied clinical medical physics · 2025
    Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Deep Learning-Based Chest CT Image Features in Diagnosis of Lung Cancer.Computational and mathematical methods in medicine · 2022
    Article
  14. Article
  15. A review of deep learning based methods for medical image multi-organ segmentation.Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) · 2021
    Review
  16. Action Recognition Using a Spatial-Temporal Network for Wild Felines.Animals : an open access journal from MDPI · 2021
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Yupei ZhangDepartment of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA, United States of America.
Zhen TianDepartment of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA, United States of America.
Yang LeiDepartment of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA, United States of America.
Tonghe WangDepartment of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA, United States of America.
Pretesh PatelDepartment of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA, United States of America.
Ashesh B JaniDepartment of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA, United States of America.
Walter J CurranDepartment of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA, United States of America.
Tian LiuDepartment of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA, United States of America.
Xiaofeng YangDepartment of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA, United States of America.ORCID 0000-0001-9023-5855
Emory University · US

Funding

Multiparametric MRI-guided Prostate HDR Brachytherapy with Focal Tumor BoostR01CA215718 · NCI · EMORY UNIVERSITY · PI YANG, XIAOFENG · 2018 to 2022
$1.8M
NCI NIH HHS R01 CA215718
6 · The paper itself

Abstract

Multi-needle localization in ultrasound (US) images is a crucial step of treatment planning for US-guided prostate brachytherapy. However, current computer-aided technologies are mostly focused on single-needle digitization, while manual digitization is labor intensive and time consuming. In this paper, we proposed a deep learning-based workflow for fast automatic multi-needle digitization, including needle shaft detection and needle tip detection. The major workflow is composed of two components: a large margin mask R-CNN model (LMMask R-CNN), which adopts the lager margin loss to reformulate Mask R-CNN for needle shaft localization, and a needle based density-based spatial clustering of application with noise algorithm which integrates priors to model a needle in an iteration for a needle shaft refinement and tip detections. Besides, we use the skipping connection in neural network architecture to improve the supervision in hidden layers. Our workflow was evaluated on 23 patients who underwent US-guided high-dose-rate (HDR) prostrate brachytherapy with 339 needles being tested in total. Our method detected 98% of the needles with 0.091 ± 0.043 mm shaft error and 0.330 ± 0.363 mm tip error. Compared with only using Mask R-CNN and only using LMMask R-CNN, the proposed method gains a significant improvement on both shaft error and tip error. The proposed method automatically digitizes needles per patient with in a second. It streamlines the workflow of transrectal ultrasound-guided HDR prostate brachytherapy and paves the way for the development of real-time treatment planning system that is expected to further elevate the quality and outcome of HDR prostate brachytherapy.

Indexed as

Deep LearningNeedlesAutomationBrachytherapyHumansMaleProstatic NeoplasmsRadiotherapy, Image-GuidedUltrasonography

Identifiers

PMID32640435
PMCPMC11758238
OpenAlexW3041581978

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.