Evidence map›Paper›PMID 32640274›Full record

ArticleGenomics2020

SARS-CoV2 envelope protein: non-synonymous mutations and its consequences.

Sk Sarif Hassan, Pabitra Pal Choudhury, Bidyut Roy

Abstract read
In one paragraph

Article in Genomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. SARS-CoV-2 E protein: Pathogenesis and potential therapeutic development.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2023
    Review
  7. Article
  8. Iranian journal of basic medical sciences · 2022
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. A unique view of SARS-CoV-2 through the lens of ORF8 protein.Computers in biology and medicine · 2021
    Article
  18. Clade GR and clade GH isolates of SARS-CoV-2 in Asia show highest amount of SNPs.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2021
    Article
  19. Article
  20. Genome composition and genetic characterization of SARS-CoV-2.Saudi journal of biological sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sk Sarif HassanDepartment of Mathematics, Pingla Thana Mahavidyalaya, Maligram, Paschim Medinipur, 721140, West Bengal, India. Electronic address: sarimif@gmail.com.
Pabitra Pal ChoudhuryApplied Statistics Unit, Indian Statistical Institute, Kolkata 700108, West Bengal, India. Electronic address: pabitra@isical.ac.in.
Bidyut RoyHuman Genetics Unit, Indian Statistical Institute, Kolkata 700108, West Bengal, India. Electronic address: broy@isical.ac.in.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the NCBI database, as on June 6, 2020, total number of available complete genome sequences of SARS-CoV2 across the world is 3617. The envelope (E) protein of SARS-CoV2 possesses several non-synonymous mutations over the transmembrane and C-terminus domains in 15 (0.414%) genomes among 3617 SARS-CoV2 genomes, analyzed. More precisely, 10(0.386%) out of 2588 genomes from the USA, 3(0.806%) from Asia, 1 (0.348%) from Europe and 1 (0.274%) from Oceania contained the missense mutations over the E-protein of SARS-CoV2 genomes. The C-terminus motif DLLV has been to DFLV and YLLV in the proteins from QJR88103 (Australia: Victoria) and QKI36831 (China: Guangzhou) respectively, which might affect the binding of this motif with the host protein PALS1.

Indexed as

MutationCoronavirus Envelope ProteinsCOVID-19Genome, ViralHumansMembrane ProteinsNucleoside-Phosphate KinaseSARS-CoV-2Coronavirus Envelope Proteinsenvelope protein, SARS-CoV-2Membrane ProteinsMPP5 protein, humanNucleoside-Phosphate KinaseCOVID-19Envelope proteinNon-synonymous mutationsSARS-CoV2

Identifiers

PMID32640274
PMCPMC7335631

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.