Evidence map›Paper›PMID 32640255›Full record

ArticleAmerican journal of ophthalmology2020

Sex Differences in the Repair of Retinal Detachments in the United States.

Natalia F Callaway, Daniel Vail, Ahmad Al-Moujahed, Cassie Ludwig, Marco H Ji, Vinit B Mahajan, Suzann Pershing, Darius M Moshfeghi

Open access · greenAbstract read
In one paragraph

Article in American journal of ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.8field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Rhegmatogenous retinal detachment repair-does age, sex, and lens status make a difference?Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022
    Article
  9. Article
  10. Pneumatic retinopexy: an update.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022
    Review
  11. Characteristics of spontaneous reattachment of rhegmatogenous retinal detachment: optical coherence tomography features and follow-up outcomes.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021
    Article
  12. Article
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  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Natalia F CallawayByers Eye Institute at the Stanford University School of Medicine, Palo Alto, California, USA. Electronic address: ncallaway@stanford.edu.
Daniel VailByers Eye Institute at the Stanford University School of Medicine, Palo Alto, California, USA.
Ahmad Al-MoujahedByers Eye Institute at the Stanford University School of Medicine, Palo Alto, California, USA.
Cassie LudwigByers Eye Institute at the Stanford University School of Medicine, Palo Alto, California, USA.
Marco H JiByers Eye Institute at the Stanford University School of Medicine, Palo Alto, California, USA.
Vinit B MahajanByers Eye Institute at the Stanford University School of Medicine, Palo Alto, California, USA; Veterans Affairs Palo Alto Health Care System, Palo Alto, California, USA.
Suzann PershingByers Eye Institute at the Stanford University School of Medicine, Palo Alto, California, USA; Veterans Affairs Palo Alto Health Care System, Palo Alto, California, USA.
Darius M MoshfeghiByers Eye Institute at the Stanford University School of Medicine, Palo Alto, California, USA.
Smith-Kettlewell Eye Research Institute · USVA Palo Alto Health Care System · US

Funding

Stanford Vision Research CoreP30EY026877 · NEI · STANFORD UNIVERSITY · PI Jeffrey L Goldberg · 2017 to 2026
$8.0M
Gene Silencing and Gene Editing in PhototransductionR01EY024698 · NEI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Stephen H Tsang · 2015 to 2026
$4.7M
Structure and Function of Calpain-5R01EY024665 · NEI · UNIVERSITY OF IOWA · PI MAHAJAN, VINIT B · 2015 to 2019
$1.9M
Mechanistic Studies on Regenerative Medicine Approaches to Childhood BlindnessR01EY026682 · NEI · UNIVERSITY OF IOWA · PI BASSUK, ALEXANDER G, MAHAJAN, VINIT B · 2016 to 2019
$1.6M
Mechanism-based therapies for photoreceptor degenerationR01EY025225 · NEI · UNIVERSITY OF IOWA · PI MAHAJAN, VINIT B · 2015 to 2018
$1.3M
NEI NIH HHS P30 EY026877NEI NIH HHS R01 EY024665NEI NIH HHS R01 EY024698NEI NIH HHS R01 EY025225NEI NIH HHS R01 EY026682
6 · The paper itself

Abstract

purposeTo investigate differences between women and men in the repair of rhegmatogenous retinal detachments (RRDs) in the United States.

designRetrospective cohort study.

methodsSetting: A large insurance claims database.

participantsSubjects with an incident RRD between 2007 and 2015. DATA: Demographic data, comorbid ocular conditions associated with RRD, systemic comorbidities, and surgical intervention (pneumatic retinopexy [PR], pars plana vitrectomy [PPV], laser barricade, or scleral buckle [SB]) were collected.

main outcome measuresOdds of receipt of surgical intervention for incident RRD, time to repair, type of intervention, and the rate of reoperation by sex.

resultsThe study period included 133 million eligible records with 61,071 cases of incident RRD among which 43% (n = 26,289) were women. The primary outcome model had 23,933 confirmed RRD cases with a 93% retinal detachment repair rate. Women had 34% reduced odds of receipt of surgical repair of an RRD (odds ratio [OR] 0.66, 95% confidence interval [CI] 0.59, 0.73; P < .001) after adjusting for confounders. This effect persisted in all sensitivity models. Among patients who received repair, women were more often delayed (0.17 days, P = .04). Women were more likely to undergo primary laser barricade (relative risk ratio [RRR] 1.68, P < .001), primary SB (RRR 1.15, P < .001), and PR (RRR 1.07, P < .04) than men. The odds of reoperation were lower in women (OR 0.91, 95% CI 0.85, 0.96; P = .002) after adjustment.

conclusionsInsured women are less likely than insured men to receive surgical intervention for an RRD. Based on the results of this study, if the odds of repair were equal between women and men in the United States, then 781 more women would receive surgery each year, or 7,029 more during the study period. Women are more likely to have the repair performed with scleral buckle, laser barricade, and pneumatic retinopexy. The reason for these sex differences in RRD repair remains unknown and requires further investigation.

Indexed as

CryosurgeryScleral BucklingVitrectomyAdultAgedDatabases, FactualFemaleHealthcare DisparitiesHumansMaleMiddle AgedOdds RatioReoperationRetinal DetachmentRetrospective StudiesSex Factors

Identifiers

PMID32640255
PMCPMC10832663
OpenAlexW3039113619

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.