ArticleHypertension (Dallas, Tex. : 1979)2020
Cardiovascular End Points and Mortality Are Not Closer Associated With Central Than Peripheral Pulsatile Blood Pressure Components.
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Article in Hypertension (Dallas, Tex. : 1979), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 4 of them syntheses that pooled it.
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26citing papers in PubMed, 4 pooled it
4.6field-weighted citation impact, top 4% of its field
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 4 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Association of cardiovascular events with central systolic blood pressure: A systemic review and meta-analysis.Journal of clinical hypertension (Greenwich, Conn.) · 2024Pooled it
- Risk Stratification by Cross-Classification of Central and Brachial Systolic Blood Pressure.Hypertension (Dallas, Tex. : 1979) · 2022Pooled it
- The International Database of Central Arterial Properties for Risk Stratification: Research Objectives and Baseline Characteristics of Participants.American journal of hypertension · 2022Pooled it
- The effectiveness and safety of isometric resistance training for adults with high blood pressure: a systematic review and meta-analysis.Hypertension research : official journal of the Japanese Society of Hypertension · 2021Pooled it
- Personalised hypertension management with accurate blood pressure measurement: much achieved, much more to do.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Article
- 24-hour isolated aortic systolic hypertension phenotype and its association with carotid and cardiac damage: the SAFAR study.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Article
- Chinese Guidelines for the Prevention and Treatment of Hypertension (2024 revision).Journal of geriatric cardiology : JGC · 2025Article
- Association Between Changes in Central Blood Pressure and Peripheral Blood Pressure With New-Onset Hypertension in a Chinese Community-Based Population.Journal of clinical hypertension (Greenwich, Conn.) · 2024Article
- Another step forward in the introduction of aortic systolic blood pressure assessment into clinical practice?Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
- Vascular phenotypes in early hypertension.Journal of human hypertension · 2023Article
- Non-Invasive Estimation of Central Systolic Blood Pressure by Radial Tonometry: A Simplified Approach.Journal of personalized medicine · 2023Article
- Hypertension in China: epidemiology and treatment initiatives.Nature reviews. Cardiology · 2023Review
- Brachial and central hypertension in relation to coronary stenosis in patients with coronary angiography.Journal of clinical hypertension (Greenwich, Conn.) · 2023Article
- What did we learn from the International Databases on Ambulatory and Home Blood Pressure in Relation to Cardiovascular Outcome?Hypertension research : official journal of the Japanese Society of Hypertension · 2023Review
- The acute adaptation of skin microcirculatory perfusionFrontiers in physiology · 2023Article
- The Relationship of Vascular Aging to Reduced Cognitive Function: Pulsatile and Steady State Arterial Hemodynamics.Pulse (Basel, Switzerland) · 2022Review
- Pre-Frailty Phenotype and Arterial Stiffness in Older Adults Free of Cardiovascular Diseases.International journal of environmental research and public health · 2022Article
- Central hypertension is a non-negligible cardiovascular risk factor.Journal of clinical hypertension (Greenwich, Conn.) · 2022Review
- Twenty-Four-Hour Central (Aortic) Systolic Blood Pressure: Reference Values and Dipping Patterns in Untreated Individuals.Hypertension (Dallas, Tex. : 1979) · 2022Article
- Comparison of Brachial Blood Pressure and Central Blood Pressure in Attended, Unattended, and Unattended Standing Situations.Hypertension research : official journal of the Japanese Society of Hypertension · 2021Article
Corrections and comments
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Authors and funding
33 authors at 18 institutions in 10 countries.
Qi-Fang Huang *From the Center for Epidemiological Studies and Clinical Trials and Center for Vascular Evaluations, Shanghai Key Laboratory of Hypertension, Shanghai Institute of Hypertension, Ruijin Hospital (Q.-F.H., Y.-B.C., C.-S.S., J.-G.W., Y.L.).
Lucas S Aparicio *Shanghai Jiao Tong University School of Medicine, China; Servicio de Clínica Médica, Sección Hipertensión Arterial, Hospital Italiano de Buenos Aires, Argentina (L.S.A., J.B.).
Lutgarde ThijsResearch Unit Hypertension and Cardiovascular Epidemiology (L.T., F.-F.W., J.D.M., Z.-Y.Z., J.A.S.), KU Leuven Department of Cardiovascular Sciences, University of Leuven, Belgium.
Fang-Fei WeiResearch Unit Hypertension and Cardiovascular Epidemiology (L.T., F.-F.W., J.D.M., Z.-Y.Z., J.A.S.), KU Leuven Department of Cardiovascular Sciences, University of Leuven, Belgium.
Jesus D MelgarejoResearch Unit Hypertension and Cardiovascular Epidemiology (L.T., F.-F.W., J.D.M., Z.-Y.Z., J.A.S.), KU Leuven Department of Cardiovascular Sciences, University of Leuven, Belgium.
Yi-Bang ChengFrom the Center for Epidemiological Studies and Clinical Trials and Center for Vascular Evaluations, Shanghai Key Laboratory of Hypertension, Shanghai Institute of Hypertension, Ruijin Hospital (Q.-F.H., Y.-B.C., C.-S.S., J.-G.W., Y.L.).
Chang-Sheng ShengFrom the Center for Epidemiological Studies and Clinical Trials and Center for Vascular Evaluations, Shanghai Key Laboratory of Hypertension, Shanghai Institute of Hypertension, Ruijin Hospital (Q.-F.H., Y.-B.C., C.-S.S., J.-G.W., Y.L.).
Wen-Yi YangDepartment of Cardiology, Shanghai General Hospital (W.-Y.Y.).
Natasza Gilis-MalinowskaHypertension Unit, Department of Hypertension and Diabetology, Medical University of Gdańsk, Poland (N.G.-M., K.N.).
José BoggiaShanghai Jiao Tong University School of Medicine, China; Servicio de Clínica Médica, Sección Hipertensión Arterial, Hospital Italiano de Buenos Aires, Argentina (L.S.A., J.B.).
Teemu J NiiranenPopulation Studies Unit, Department of Chronic Disease Prevention, National Institute for Health and Welfare, Turku, Finland (T.J.N., A.M.J.).
Wiktoria WojciechowskaFirst Department of Cardiology, Interventional Electrocardiology and Hypertension, Jagiellonian University Medical College, Kraków, Poland (W.W., K.S.-S., D.C., K.K.-J.).
Katarzyna Stolarz-SkrzypekFirst Department of Cardiology, Interventional Electrocardiology and Hypertension, Jagiellonian University Medical College, Kraków, Poland (W.W., K.S.-S., D.C., K.K.-J.).
Jessica BarochinerCentro de Nefrología and Departamento de Fisiopatología, Hospital de Clínicas, Universidad de la República, Montevideo, Uruguay (J.B.).
Daniel AckermannDepartment of Nephrology and Hypertension, Inselspital, Bern University Hospital, University of Bern, Switzerland (D.A.).
Valérie TikhonoffDepartment of Medicine, University of Padua, Italy (V.T., E.C.).
Belen PonteDivision of Nephrology, University Hospital of Geneva, Geneva, Switzerland (B.P.).
Menno PruijmService of Nephrology and Hypertension, Lausanne University Hospital and University of Lausanne, Switzerland (M.P.).
Edoardo CasigliaDepartment of Medicine, University of Padua, Italy (V.T., E.C.).
Krzysztof NarkiewiczHypertension Unit, Department of Hypertension and Diabetology, Medical University of Gdańsk, Poland (N.G.-M., K.N.).
Jan FilipovskýFaculty of Medicine, Charles University, Pilsen, Czech Republic (J.F.).
Danuta CzarneckaFirst Department of Cardiology, Interventional Electrocardiology and Hypertension, Jagiellonian University Medical College, Kraków, Poland (W.W., K.S.-S., D.C., K.K.-J.).
Kalina Kawecka-JaszczFirst Department of Cardiology, Interventional Electrocardiology and Hypertension, Jagiellonian University Medical College, Kraków, Poland (W.W., K.S.-S., D.C., K.K.-J.).
Antti M JulaPopulation Studies Unit, Department of Chronic Disease Prevention, National Institute for Health and Welfare, Turku, Finland (T.J.N., A.M.J.).
Murielle BochudCenter for Primary Care and Public Health (M.B.), Unisanté, University of Lausanne, Switzerland.
Thomas VanasscheCentre for Molecular and Vascular Biology (T.V., P.V.), KU Leuven Department of Cardiovascular Sciences, University of Leuven, Belgium.
Peter VerhammeCentre for Molecular and Vascular Biology (T.V., P.V.), KU Leuven Department of Cardiovascular Sciences, University of Leuven, Belgium.
Harry A J Struijker-BoudierDepartment of Pharmacology and Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, the Netherlands (H.A.J.S.-B.).
Ji-Guang WangFrom the Center for Epidemiological Studies and Clinical Trials and Center for Vascular Evaluations, Shanghai Key Laboratory of Hypertension, Shanghai Institute of Hypertension, Ruijin Hospital (Q.-F.H., Y.-B.C., C.-S.S., J.-G.W., Y.L.).
Zhen-Yu Zhang *Research Unit Hypertension and Cardiovascular Epidemiology (L.T., F.-F.W., J.D.M., Z.-Y.Z., J.A.S.), KU Leuven Department of Cardiovascular Sciences, University of Leuven, Belgium.
Yan Li *From the Center for Epidemiological Studies and Clinical Trials and Center for Vascular Evaluations, Shanghai Key Laboratory of Hypertension, Shanghai Institute of Hypertension, Ruijin Hospital (Q.-F.H., Y.-B.C., C.-S.S., J.-G.W., Y.L.).
Jan A Staessen *Research Unit Hypertension and Cardiovascular Epidemiology (L.T., F.-F.W., J.D.M., Z.-Y.Z., J.A.S.), KU Leuven Department of Cardiovascular Sciences, University of Leuven, Belgium.
IDCARS (International Database of Central Arterial Properties for Risk Stratification) Investigators
KU Leuven · BERuijin Hospital · CNJagiellonian University · PLMaastricht University · NLGdańsk Medical University · PLUniversity of Padua · ITCentre universitaire de médecine générale et santé publique, Lausanne · CHCharles University · CZFinnish Institute for Health and Welfare · FIHospital Italiano de Buenos Aires · ARNorth Atlantic Treaty Organization · BEShanghai First People's Hospital · CNUniversidad de la República de Uruguay · UYUniversity Hospital of Geneva · CHUniversity of Bern · CHUniversity of Lausanne · CHUniversity of Turku · FIShanghai Jiao Tong University · CN
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pulsatile blood pressure (BP) confers cardiovascular risk. Whether associations of cardiovascular end points are tighter for central systolic BP (cSBP) than peripheral systolic BP (pSBP) or central pulse pressure (cPP) than peripheral pulse pressure (pPP) is uncertain. Among 5608 participants (54.1% women; mean age, 54.2 years) enrolled in nine studies, median follow-up was 4.1 years. cSBP and cPP, estimated tonometrically from the radial waveform, averaged 123.7 and 42.5 mm Hg, and pSBP and pPP 134.1 and 53.9 mm Hg. The primary composite cardiovascular end point occurred in 255 participants (4.5%). Across fourths of the cPP distribution, rates increased exponentially (4.1, 5.0, 7.3, and 22.0 per 1000 person-years) with comparable estimates for cSBP, pSBP, and pPP. The multivariable-adjusted hazard ratios, expressing the risk per 1-SD increment in BP, were 1.50 (95% CI, 1.33-1.70) for cSBP, 1.36 (95% CI, 1.19-1.54) for cPP, 1.49 (95% CI, 1.33-1.67) for pSBP, and 1.34 (95% CI, 1.19-1.51) for pPP (
Indexed as
AdultAgedBlood PressureBlood Pressure DeterminationCardiovascular DiseasesFemaleHeart Disease Risk FactorsHumansHypertensionMaleMiddle Agedblood pressuremorbiditymortalitypopulationrisk
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