Evidence map›Paper›PMID 32639860›Full record

ArticleStroke2020

Effect of COVID-19 on Emergent Stroke Care: A Regional Experience.

Jessica Hsiao, Emily Sayles, Eleni Antzoulatos, Robert J Stanton, Heidi Sucharew, Joseph P Broderick, Stacie L Demel, Matthew L Flaherty, Aaron W Grossman, Charles Kircher and 8 more

Open access · greenAbstract read
In one paragraph

Article in Stroke, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

  1. Stroke network performance during the first COVID-19 pandemic stage: A meta-analysis based on stroke network models.International journal of stroke : official journal of the International Stroke Society · 2021
    Pooled it
  2. Global stroke statistics 2023: Availability of reperfusion services around the world.International journal of stroke : official journal of the International Stroke Society · 2024
    Review
  3. Article
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  9. Stroke admissions during the COVID-19 pandemic: a single-center retrospective analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
    Article
  10. Observational
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  14. Stroke management during the coronavirus disease 2019 (COVID-19) pandemic: experience from three regions of the north east of Italy (Veneto, Friuli-Venezia-Giulia, Trentino-Alto-Adige).Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
    Article
  15. COVID-19 and ischemic stroke.European journal of neurology · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 2 countries.

Jessica HsiaoDepartment of Neurology (J.H., E.S., E.A., R. J. S., J.P.B., S. L. D., M.L.F., A. W. G., P.S., P.K.), University of Cincinnati, OH.
Emily SaylesDepartment of Neurology (J.H., E.S., E.A., R. J. S., J.P.B., S. L. D., M.L.F., A. W. G., P.S., P.K.), University of Cincinnati, OH.
Eleni AntzoulatosDepartment of Neurology (J.H., E.S., E.A., R. J. S., J.P.B., S. L. D., M.L.F., A. W. G., P.S., P.K.), University of Cincinnati, OH.
Robert J StantonDepartment of Neurology (J.H., E.S., E.A., R. J. S., J.P.B., S. L. D., M.L.F., A. W. G., P.S., P.K.), University of Cincinnati, OH.
Heidi SucharewDivision of Biostatistics (H.S.), Cincinnati Children's Hospital Medical Center, OH.
Joseph P BroderickDepartment of Neurology (J.H., E.S., E.A., R. J. S., J.P.B., S. L. D., M.L.F., A. W. G., P.S., P.K.), University of Cincinnati, OH.
Stacie L DemelDepartment of Neurology (J.H., E.S., E.A., R. J. S., J.P.B., S. L. D., M.L.F., A. W. G., P.S., P.K.), University of Cincinnati, OH.
Matthew L FlahertyDepartment of Neurology (J.H., E.S., E.A., R. J. S., J.P.B., S. L. D., M.L.F., A. W. G., P.S., P.K.), University of Cincinnati, OH.
Aaron W GrossmanDepartment of Neurology (J.H., E.S., E.A., R. J. S., J.P.B., S. L. D., M.L.F., A. W. G., P.S., P.K.), University of Cincinnati, OH.
Charles KircherDepartment of Emergency Medicine (C.K., N.K., K.B.W., O.A.), University of Cincinnati, OH.
Natalie KreitzerDepartment of Emergency Medicine (C.K., N.K., K.B.W., O.A.), University of Cincinnati, OH.
Katrina PearisoDivision of Neurology (K.P.), Cincinnati Children's Hospital Medical Center, OH.
Charles J PrestigiacomoDepartment of Neurosurgery (C. J. P.), University of Cincinnati, OH.
Peyman ShiraniDepartment of Neurology (J.H., E.S., E.A., R. J. S., J.P.B., S. L. D., M.L.F., A. W. G., P.S., P.K.), University of Cincinnati, OH.
Kyle B WalshDepartment of Emergency Medicine (C.K., N.K., K.B.W., O.A.), University of Cincinnati, OH.
Holly LamptonDepartment of Communications, Hamilton County, Cincinnati, OH (H.L.).
Opeolu AdeoyeDepartment of Emergency Medicine (C.K., N.K., K.B.W., O.A.), University of Cincinnati, OH.
Pooja KhatriDepartment of Neurology (J.H., E.S., E.A., R. J. S., J.P.B., S. L. D., M.L.F., A. W. G., P.S., P.K.), University of Cincinnati, OH.
S.P.E.C.I.E.S. · USUniversity of Cincinnati · USCincinnati Children's Hospital Medical Center · USHamilton County Coroner · USWalsh University · US

Funding

Cerebrovascular Fellowship Training ProgramT32NS047996 · NINDS · UNIVERSITY OF CINCINNATI · PI Joseph Paul Broderick, Stacie Demel · 2006 to 2026
$3.7M
Ohio Valley Regional Coordinating Center for NINDS Stroke Trial NetworkU24NS107241 · NINDS · UNIVERSITY OF CINCINNATI · PI Stacie Demel, Eva Mistry · 2018 to 2026
$2.9M
Cincinnati Regional Coordinating Stroke Center (Cincinnati RCC)U10NS086512 · NINDS · UNIVERSITY OF CINCINNATI · PI KHATRI, POOJA, KLEINDORFER, DAWN O · 2013 to 2017
$1.9M
NINDS NIH HHS T32 NS047996NINDS NIH HHS U10 NS086512NINDS NIH HHS U24 NS107241
6 · The paper itself

Abstract

background and purposeAnecdotal evidence suggests that the coronavirus disease 2019 (COVID-19) pandemic mitigation efforts may inadvertently discourage patients from seeking treatment for stroke with resultant increased morbidity and mortality. Analysis of regional data, while hospital capacities for acute stroke care remained fully available, offers an opportunity to assess this. We report regional Stroke Team acute activations and reperfusion treatments during COVID-19 mitigation activities.

methodsUsing case log data prospectively collected by a Stroke Team exclusively serving ≈2 million inhabitants and 30 healthcare facilities, we retrospectively reviewed volumes of consultations and reperfusion treatments for acute ischemic stroke. We compared volumes before and after announcements of COVID-19 mitigation measures and the prior calendar year.

resultsCompared with the 10 weeks prior, stroke consultations declined by 39% (95% CI, 32%-46%) in the 5 weeks after announcement of statewide school and restaurant closures in Ohio, Kentucky, and Indiana. Results compared with the prior year and time trend analyses were consistent. Reperfusion treatments also appeared to decline by 31% (95% CI, 3%-51%), and specifically thrombolysis by 33% (95% CI, 4%-55%), but this finding had less precision.

conclusionsUpon the announcement of measures to mitigate COVID-19, regional acute stroke consultations declined significantly. Reperfusion treatment rates, particularly thrombolysis, also appeared to decline qualitatively, and this finding requires further study. Urgent public education is necessary to mitigate a possible crisis of avoiding essential emergency care due to COVID-19.

Indexed as

Coronavirus InfectionsCOVID-19HumansIndianaKentuckyOhioPandemicsPatient Care TeamPneumonia, ViralProspective StudiesReferral and ConsultationReperfusionStrokeThrombectomyThrombolytic TherapyTime-to-Treatmentpandemicsreperfusionrestaurantsstrokeviruses

Identifiers

PMID32639860
PMCPMC7359904
OpenAlexW3041512554

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.