ArticleCancer medicine2020
Body mass index trajectories and prostate cancer risk: Results from the EPICAP study.
Article in Cancer medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Life Course Trajectories of Body Mass Index and Risk of Cancer in Adulthood: Systematic Review and Meta-Analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026Pooled it
- Weight trajectories throughout adulthood and prostate cancer incidence, aggressiveness, and death in 258 494 men.Journal of the National Cancer Institute · 2026Article
- Association of visceral obesity indicators with prostate cancer: a cross-sectional study from Xinjiang.Frontiers in oncology · 2025Article
- Adiposity assessed close to diagnosis and prostate cancer prognosis in the EPIC study.JNCI cancer spectrum · 2024Article
- Clustering and trajectories of key noncommunicable disease risk factors in Norway: the NCDNOR project.Scientific reports · 2023Article
- Associations between Body Mass Index and Prostate Cancer: The Impact on Progression-Free Survival.Medicina (Kaunas, Lithuania) · 2023Article
- Association between genetically proxied PCSK9 inhibition and prostate cancer risk: A Mendelian randomisation study.PLoS medicine · 2023Article
- Early prediction of prostate cancer risk in younger men using polygenic risk scores and electronic health records.Cancer medicine · 2023Article
- Clinical Predictors of Grade Group Upgrading for Radical Prostatectomy Specimens Compared to Those of Preoperative Needle Biopsy Specimens.Diagnostics (Basel, Switzerland) · 2022Article
- Association between obesity and frequency of high-grade prostate cancer on biopsy in men: A single-center retrospective study.Molecular and clinical oncology · 2022Article
- Longitudinal trajectories of lifetime body shape and prostate cancer angiogenesis.European journal of epidemiology · 2022Article
- Personalized 5-Year Prostate Cancer Risk Prediction Model in Korea Based on Nationwide Representative Data.Journal of personalized medicine · 2021Article
- Body mass index trajectories and prostate cancer risk: Results from the EPICAP study.Cancer medicine · 2020Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Elevated body mass index (BMI) has been inconsistently associated with prostate cancer occurrence but it has been suggested that life course adulthood obesity may be associated with an increased risk of prostate cancer. However, few studies have investigated lifetime BMI and prostate cancer risk. We analyzed life course BMI trajectories on prostate cancer risk based on data from the Epidemiological study of Prostate Cancer (EPICAP). We included in our analyses 781 incident prostate cancer cases and 829 controls frequency matched by age. Participants were asked about their weight every decade from age 20 to two years before reference date. BMI trajectories were determined using group-based trajectory modeling to identify groups of men with similar patterns of BMI changes. We identified five BMI trajectories groups. Men with a normal BMI at age 20 developing overweight or obesity during adulthood were at increased risk of aggressive prostate cancer compared to men who maintained a normal BMI. Our results suggest that BMI trajectories resulting in overweight or obesity during adulthood are associated with an increased risk of aggressive prostate cancer, particularly in never smokers, emphasizing the importance of maintaining a healthy BMI throughout adulthood.
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