ArticleMicrobial biotechnology2020
Gut microbiota composition before infection determines the Salmonella super- and low-shedder phenotypes in chicken.
Article in Microbial biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- Gut microbiota signatures associated with the development of Salmonella Typhimurium super-shedders in broiler chickens.Poultry science · 2026Article
- Recurrent phage treatment of Salmonella-infected chickens transiently reshapes gut microbiota composition and function.Veterinary research · 2026Article
- The immune response modulated by inoculation of commensal bacteria at birth impacts the gut microbiota and preventsGut microbes · 2025Article
- Development and characterization of a saturated transposon mutant library ofMicrobiology resource announcements · 2025Article
- Superspreaders have lower gut microbial alpha-diversity and distinct gut microbial composition in a natural rodent population.Animal microbiome · 2025Article
- Nanotechnological Plastic Flooring: Implications for Broiler Chicken Performance, Health, and Carcass Quality.Veterinary sciences · 2025Article
- A Two Bacteriocinogenic Ligilactobacillus Strain Association Inhibits Growth, Adhesion, and Invasion of Salmonella in a Simulated Chicken Gut Environment.Probiotics and antimicrobial proteins · 2024Article
- The effect and potential mechanism of inulin combined with fecal microbiota transplantation on early intestinal immune function in chicks.Scientific reports · 2024Article
- Dust sprinkling as an effective method for infecting layer chickens with wild-type Salmonella Typhimurium and changes in host gut microbiota.Environmental microbiology reports · 2024Article
- Combination of autochthonousFrontiers in microbiology · 2024Article
- Phenotype Alterations in the Cecal Ecosystem Involved in the Asymptomatic Intestinal Persistence of ParatyphoidAnimals : an open access journal from MDPI · 2023Review
- Article
- Application of Eugenol in Poultry to ControlVeterinary sciences · 2023Review
- Super Shedding in Enteric Pathogens: A Review.Microorganisms · 2022Review
- Effect ofAnimals : an open access journal from MDPI · 2022Article
- Safety of bivalent live attenuated Salmonella vaccine and its protection against bacterial shedding and tissue invasion in layers challenged with Salmonella.Poultry science · 2022Article
- Long-chain glucomannan supplementation modulates immune responsiveness, as well as intestinal microbiota, and impacts infection of broiler chickens with Salmonella enterica serotype Enteritidis.Veterinary research · 2022Article
- Assessment of listing and categorisation of animal diseases within the framework of the Animal Health Law (Regulation (EU) No 2016/429): antimicrobial-resistantEFSA journal. European Food Safety Authority · 2022Article
- Differences in caecal microbiota composition and Salmonella carriage between experimentally infected inbred lines of chickens.Genetics, selection, evolution : GSE · 2022Article
- Gastrointestinal Dynamics of Non-Encapsulated and MicroencapsulatedAnimals : an open access journal from MDPI · 2022Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heterogeneity of infection and extreme shedding patterns are common features of animal infectious diseases. Individual hosts that are super-shedders are key targets for control strategies. Nevertheless, the mechanisms associated with the emergence of super-shedders remain largely unknown. During chicken salmonellosis, a high heterogeneity of infection is observed when animal-to-animal cross-contaminations and reinfections are reduced. We hypothesized that unlike super-shedders, low-shedders would be able to block the first Salmonella colonization thanks to a different gut microbiota. The present study demonstrates that (i) axenic and antibiotic-treated chicks are more prone to become super-shedders; (ii) super or low-shedder phenotypes can be acquired through microbiota transfer; (iii) specific gut microbiota taxonomic features determine whether the chicks develop a low- and super-shedder phenotype after Salmonella infection in isolator; (iv) partial protection can be conferred by inoculation of four commensal bacteria prior to Salmonella infection. This study demonstrates the key role plays by gut microbiota composition in the heterogeneity of infection and pave the way for developing predictive biomarkers and protective probiotics.
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