Evidence map›Paper›PMID 32639479›Full record

ArticlePublic health action2020

Tuberculosis preventive treatment opportunities at antiretroviral therapy initiation and follow-up visits.

T Agizew, D Surie, J E Oeltmann, M Letebele, S Pals, U Mathebula, A Mathoma, M Kassa, S Hamda, P Pono and 4 more

Open access · diamondAbstract read
In one paragraph

Article in Public health action, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.0field-weighted citation impact, top 61% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Intradermal comparative cervical tuberculin test in the diagnosis of caprine tuberculosis.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 5 countries.

T AgizewCenters for Disease Control and Prevention (CDC), Gaborone, Botswana.
D SurieDivision of Global HIV/AIDS and Tuberculosis, CDC, Atlanta, GA, USA.
J E OeltmannDivision of Global HIV/AIDS and Tuberculosis, CDC, Atlanta, GA, USA.
M LetebeleCenters for Disease Control and Prevention (CDC), Gaborone, Botswana.
S PalsDivision of Global HIV/AIDS and Tuberculosis, CDC, Atlanta, GA, USA.
U MathebulaCenters for Disease Control and Prevention (CDC), Gaborone, Botswana.
A MathomaCenters for Disease Control and Prevention (CDC), Gaborone, Botswana.
M KassaDepartment of Anaesthesia and Critical Care, University of Botswana, Gaborone, Botswana.
S HamdaDepartment of Family Medicine and Public Health, Faculty of Medicine, University of Botswana, Gaborone, Botswana.
P PonoDepartment of HIV/AIDS Prevention and Care, Ministry of Health and Wellness, Gaborone, Botswana.
G Rankgoane-PonoNational Tuberculosis Control Programme, Ministry of Health and Wellness, Gaborone, Botswana.
R BoydCenters for Disease Control and Prevention (CDC), Gaborone, Botswana.
A AuldDivision of Global HIV/AIDS and Tuberculosis, CDC, Atlanta, GA, USA.
A FinlayCenters for Disease Control and Prevention (CDC), Gaborone, Botswana.
AIDS United · USUniversity of Botswana · BWCDC Foundation · USCenters for Disease Control and Prevention · USMinistry of Health · BWNational Tuberculosis Institute · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

settingTwenty-two clinics providing HIV care and treatment in Botswana where tuberculosis (TB) and HIV comorbidity is as high as 49%.

objectivesTo assess eligibility of TB preventive treatment (TPT) at antiretroviral therapy (ART) initiation and at four follow-up visits (FUVs), and to describe the TB prevalence and associated factors at baseline and yield of TB diagnoses at each FUV.

designA prospective study of routinely collected data on people living with HIV (PLHIV) enrolled into care for the Xpert

resultsOf 6041 PLHIV initiating ART, eligibility for TPT was 69% (4177/6041) at baseline and 93% (5408/5815); 95% (5234/5514); 96% (4869/5079); and 97% (3925/4055) at FUV1, FUV2, FUV3, and FUV4, respectively. TB prevalence at baseline was 11% and 2%, 3%, 3% and 6% at each subsequent FUV. At baseline, independent risk factors for prevalent TB were CD4 <200 cells/mm

conclusionEligibility for TPT initiation is higher at visits post-ART initiation, while most cases of active TB were identified at ART initiation. Missed opportunities for TB further compromises TB control effort among PLHIV in Botswana.

Indexed as

HIVinfectionpreventiveTBtreatment

Identifiers

PMID32639479
PMCPMC7316437
OpenAlexW3037592508

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.