Evidence map›Paper›PMID 32639473›Full record

ArticlePediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies2020

Influence of Early Extubation Location on Outcomes Following Pediatric Cardiac Surgery.

Sydney R Rooney, Christopher W Mastropietro, Brian Benneyworth, Eric M Graham, Darren Klugman, John Costello, Nancy Ghanayem, Wenying Zhang, Mousumi Banerjee, Michael Gaies

Registry-linked trialAbstract read
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In one paragraph

Article in Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07059689 (High Flow Nasal Cannula vs. Non-Invasive Ventilation in Post-Extubation Pediatric Cardiac Surgery Patients), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07059689 narecruitingnot on this mapstarted 2025, after this paper: background citation

High Flow Nasal Cannula vs. Non-Invasive Ventilation in Post-Extubation Pediatric Cardiac Surgery Patients: A Randomized Controlled Trial

TypeinterventionalSponsorIndonesia UniversityRan2025 to 2025Enrolled114ConditionsHeart Defects, Congenital, Intensive Care Units, Pediatric, Respiration, Artificial, ExtubationArmsHigh Flow Nasal Cannula (HFNC), Non-Invasive Ventilation (NIV)
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Sydney R RooneyChildren's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA.
Christopher W MastropietroDivision of Critical Care, Department of Pediatrics, Indiana University School of Medicine, Riley Hospital for Children, Indianapolis, IN.
Brian BenneyworthDivision of Critical Care, Department of Pediatrics, Indiana University School of Medicine, Riley Hospital for Children, Indianapolis, IN.
Eric M GrahamDepartment of Pediatrics, Division of Pediatric Cardiology, Medical University of South Carolina, Charleston, SC.
Darren KlugmanDepartment of Critical Care Medicine and Cardiology, Children's National Medical Center, Washington, DC.
John CostelloDepartment of Pediatrics, Division of Pediatric Cardiology, Medical University of South Carolina, Charleston, SC.
Nancy GhanayemDepartment of Pediatrics, Division of Critical Care, Texas Children's Hospital and Baylor College of Medicine, Houston, TX.
Wenying ZhangCenter for Healthcare Outcomes and Policy, University of Michigan, Ann Arbor, MI.
Mousumi BanerjeeCenter for Healthcare Outcomes and Policy, University of Michigan, Ann Arbor, MI.
Michael GaiesDepartment of Pediatrics and Communicable Disease, Division of Cardiology, C.S. Mott Children's Hospital and University of Michigan Medical School, Ann Arbor, MI.

Funding

Michigan Institute for Clinical and Health Research (MICHR)UL1TR002240 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUMENG, JULIE C, MASHOUR, GEORGE ALEXANDER · 2017 to 2022
$54.9M
Explaining Variation in Mortality after Pediatric Cardiac SurgeryK08HL116639 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GAIES, MICHAEL · 2014 to 2018
$767k
NCATS NIH HHS UL1 TR002240NHLBI NIH HHS K08 HL116639
6 · The paper itself

Abstract

objectivesEarly extubation following pediatric cardiac surgery is common, but debate exists whether location affects outcome, with some centers performing routine early extubations in the operating room (odds ratio) and others in the cardiac ICU. We aimed to define early extubation practice variation across hospitals and assess impact of location on hospital length-of-stay and other outcomes.

designSecondary analysis of the Pediatric Cardiac Critical Care Consortium registry.

settingTwenty-eight Pediatric Cardiac Critical Care Consortium hospitals. PATIENTS: Patients undergoing Society of Thoracic Surgeons-European Association for Cardio-Thoracic Surgery mortality category 1-3 operations between August 2014 and February 2018.

interventionsNone. MEASUREMENTS AND MAIN

resultsWe defined early extubation as extubation less than 6 hours after postoperative admission. Hospitals were categorized based on the proportion of their early extubation patients who underwent an odds ratio extubation. Categories included low- (< 50% of early extubation, n = 12), medium- (50%-90%, n = 8), or high- (> 90%, n = 8) frequency odds ratio early extubation centers. The primary outcome of interest was postoperative hospital length-of-stay. We analyzed 16,594 operations (9,143 early extubation, 55%). Rates of early extubation ranged from 16% to 100% across hospitals. Odds ratio early extubation rates varied from 16% to 99%. Patient characteristics were similar across hospital odds ratio early extubation categories. Early extubation rates paralleled the hospital odds ratio early extubation rates-77% patients underwent early extubation at high-frequency odds ratio extubation centers compared with 39% at low-frequency odds ratio extubation centers (p < 0.001). High- and low-frequency odds ratio early extubation hospitals had similar length-of-stay, cardiac arrest rates, and low mortality. However, high-frequency odds ratio early extubation hospitals used more noninvasive ventilation than low-frequency hospitals (15% vs. 9%; p < 0.01), but had fewer extubation failures (3.6% vs. 4.5%; p = 0.02).

conclusionsConsiderable variability exists in early extubation practices after low- and moderate-complexity pediatric cardiac surgery. In this patient population, hospital length-of-stay did not differ significantly between centers with different early extubation strategies based on location or frequency.

Indexed as

Cardiac Surgical ProceduresThoracic SurgeryAirway ExtubationChildHumansLength of StayRetrospective StudiesTime FactorsTreatment Outcome

Identifiers

PMID32639473
PMCPMC7541477

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.