Evidence map›Paper›PMID 32639040›Full record

ArticleThe EMBO journal2020

CCR5 deficiency/CCR5Δ32: resistant to HIV infection at the cost of curtailed CD4

Christoph Matti, Daniel F Legler

Open access · bronzeAbstract readComment
In one paragraph

Article in The EMBO journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. The Chemokine Receptor CCR5 Links Memory CD4Frontiers in immunology · 2021
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Christoph MattiBiotechnology Institute Thurgau (BITg), University of Konstanz, Kreuzlingen, Switzerland.
Daniel F LeglerBiotechnology Institute Thurgau (BITg), University of Konstanz, Kreuzlingen, Switzerland.ORCID 0000-0001-8610-4764
Biotechnology Institute Thurgau · CHUniversity of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Orchestrated trafficking and activation by pathogen-derived peptides define the ability of CD4

Indexed as

HIV-1HIV InfectionsCD4-Positive T-LymphocytesCeramidesHumansReceptors, CCR5CCR5 protein, humanCeramidesReceptors, CCR5

Identifiers

PMID32639040
PMCPMC7396855
OpenAlexW3040960629

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.