Evidence map›Paper›PMID 32639029›Full record

ReviewImmunology2020

The battle for iron in enteric infections.

Ana Sousa Gerós, Alison Simmons, Hal Drakesmith, Anna Aulicino, Joe N Frost

Open access · hybridAbstract readReview
In one paragraph

Review in Immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. (p)ppGpp is required for virulence ofInfection and immunity · 2024
    Article
  12. Iron from the gut: the role of divalent metal transporter 1.Journal of clinical biochemistry and nutrition · 2024
    Article
  13. Iron transport pathways in the human malaria parasiteFrontiers in cellular and infection microbiology · 2024
    Article
  14. Article
  15. Review
  16. Effects of deferoxamine on intrinsic colistin resistance ofExperimental and therapeutic medicine · 2023
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ana Sousa GerósMRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.ORCID 0000-0002-6262-755X
Alison SimmonsMRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
Hal DrakesmithMRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.ORCID 0000-0002-8503-6103
Anna AulicinoMRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.ORCID 0000-0002-3407-2796
Joe N FrostMRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
John Radcliffe Hospital · GBUniversity of Oxford · GB

Funding

Medical Research Council MC_PC_MR/S025952/1Medical Research Council MC_UU_00008/10Medical Research Council MC_UU_00008/7Medical Research Council MC_UU_12010/10Medical Research Council MC_UU_12010/7Medical Research Council MR/S036377/1Wellcome TrustWellcome Trust 219523/Z/19/Z
6 · The paper itself

Abstract

Iron is an essential element for almost all living organisms, but can be extremely toxic in high concentrations. All organisms must therefore employ homeostatic mechanisms to finely regulate iron uptake, usage and storage in the face of dynamic environmental conditions. The critical step in mammalian systemic iron homeostasis is the fine regulation of dietary iron absorption. However, as the gastrointestinal system is also home to >10

Indexed as

AnimalsClostridiaceaeGastrointestinal DiseasesGram-Positive Bacterial InfectionsHomeostasisHumansIronMicrobiotaSalmonellaSalmonella InfectionsIronClostridiagut microbiotaironnutritional immunitySalmonella

Identifiers

PMID32639029
PMCPMC7576875
OpenAlexW3040806694

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.