Evidence map›Paper›PMID 32638890›Full record

ArticleRevista da Sociedade Brasileira de Medicina Tropical2020

Confirmed Invasive Pulmonary Aspergillosis and COVID-19: the value of postmortem findings to support antemortem management.

Monique Freire Santana, Guilherme Pivoto, Márcia A Araujo Alexandre, Djane Clarys Baía-da-Silva, Mayla Gabriela da Silva Borba, Fernando Almeida Val, Jose Diego Brito-Sousa, Gisely Cardoso Melo, Wuelton Marcelo Monteiro, João Vicente Braga Souza and 10 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Revista da Sociedade Brasileira de Medicina Tropical, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 3 pooled it
1.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 3 syntheses or guidelines pooled it, 65 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Review
  7. Article
  8. Pathogens (Basel, Switzerland) · 2022
    Review
  9. Article
  10. Review
  11. Tendency in Pulmonary Aspergillosis Investigation during the COVID-19 Era: What Is Changing?International journal of environmental research and public health · 2022
    Article
  12. An overview of COVID-19 related to fungal infections: what do we know after the first year of pandemic?Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022
    Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Invasive Fungal Disease Complicating Coronavirus Disease 2019: When It Rains, It Spores.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
  18. COVID-19-Associated Pulmonary Aspergillosis (CAPA).Journal of intensive medicine · 2021
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 5 institutions in 1 country.

Monique Freire SantanaFundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, AM, Brasil.
Guilherme PivotoFundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, AM, Brasil.
Márcia A Araujo AlexandreFundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, AM, Brasil.
Djane Clarys Baía-da-SilvaFundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, AM, Brasil.
Mayla Gabriela da Silva BorbaFundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, AM, Brasil.
Fernando Almeida ValFundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, AM, Brasil.
Jose Diego Brito-SousaFundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, AM, Brasil.
Gisely Cardoso MeloFundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, AM, Brasil.
Wuelton Marcelo MonteiroFundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, AM, Brasil.
João Vicente Braga SouzaLaboratório de Micologia, Instituto Nacional de Pesquisas da Amazônia, Manaus, AM, Brasil.
Silviane Bezerra PinheiroLaboratório de Micologia, Instituto Nacional de Pesquisas da Amazônia, Manaus, AM, Brasil.
Luiz Carlos Lima FerreiraFundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, AM, Brasil.
Felipe Gomes NavecaInstituto Leônidas & Maria Deane, Fundação Oswaldo Cruz, Manaus, AM, Brasil.
Valdinete Alves NascimentoInstituto Leônidas & Maria Deane, Fundação Oswaldo Cruz, Manaus, AM, Brasil.
André Lima Guerra CoradoInstituto Leônidas & Maria Deane, Fundação Oswaldo Cruz, Manaus, AM, Brasil.
Ludhmila Abrahão HajjarUniversidade de São Paulo, São Paulo, SP, Brasil.
João Ricardo Silva NetoFundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, AM, Brasil.
George Alan Villarouco SivaInstituto Leônidas & Maria Deane, Fundação Oswaldo Cruz, Manaus, AM, Brasil.
Alessandro C PasqualottoUniversidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS, Brasil.
Marcus Vinícius Guimarães LacerdaFundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, AM, Brasil.
Fundação de Medicina Tropical · BRFundação Oswaldo Cruz · BRInstituto Nacional de Pesquisas da Amazônia · BRUniversidade de São Paulo · BRUniversidade Federal de Ciências da Saúde de Porto Alegre · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present postmortem evidence of invasive pulmonary aspergillosis (IPA) in a patient with severe COVID-19. Autopsies of COVID-19 confirmed cases were performed. The patient died despite antimicrobials, mechanical ventilation, and vasopressor support. Histopathology and peripheral blood galactomannan antigen testing confirmed IPA. Aspergillus penicillioides infection was confirmed by nucleotide sequencing and BLAST analysis. Further reports are needed to assess the occurrence and frequency of IPA in SARS-CoV-2 infections, and how they interact clinically.

Indexed as

BetacoronavirusAgedAspergillusAutopsyCoronavirus InfectionsCOVID-19Fatal OutcomeHumansInvasive Pulmonary AspergillosisLungMalePandemicsPneumonia, ViralSARS-CoV-2

Identifiers

PMID32638890
PMCPMC7341831
OpenAlexW3039181084

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.