Evidence map›Paper›PMID 32638683›Full record

ArticleEpidemiology and psychiatric sciences2020

Intermittent explosive disorder subtypes in the general population: association with comorbidity, impairment and suicidality.

K M Scott, Y A de Vries, S Aguilar-Gaxiola, A Al-Hamzawi, J Alonso, E J Bromet, B Bunting, J M Caldas-de-Almeida, A Cía, S Florescu and 14 more

Open access · goldAbstract read
In one paragraph

Article in Epidemiology and psychiatric sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
0.5field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 20 institutions in 18 countries.

K M ScottDepartment of Psychological Medicine, Dunedin School of Medicine, University of Otago, PO Box 56, Dunedin9054, New Zealand.ORCID https://orcid.org/0000-0002-3928-8377
Y A de VriesDepartment of Developmental Psychology, Rijksuniversiteit Groningen, Groningen, Netherlands.
S Aguilar-GaxiolaCenter for Reducing Health Disparities, UC Davis Health System, Sacramento, California, USA.
A Al-HamzawiCollege of Medicine, Al-Qadisiya University, Diwaniya governorate, Iraq.
J AlonsoHealth Services Research Unit, IMIM-Hospital del Mar Medical Research Institute, Barcelona, Spain.
E J BrometDepartment of Psychiatry, Stony Brook University School of Medicine, Stony Brook, New York, USA.
B BuntingSchool of Psychology, Ulster University, Londonderry, UK.
J M Caldas-de-AlmeidaLisbon Institute of Global Mental Health and Chronic Diseases Research Center (CEDOC), NOVA Medical School | Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal.ORCID https://orcid.org/0000-0003-1902-6772
A CíaAnxiety Disorders Center, Buenos Aires, Argentina.
S FlorescuNational School of Public Health, Management and Development, Bucharest, Romania.
O GurejeDepartment of Psychiatry, University College Hospital, Ibadan, Nigeria.ORCID https://orcid.org/0000-0003-0094-5947
C-Y HuShenzhen Institute of Mental Health & Shenzhen Kangning Hospital, Shenzhen, China.
E G KaramDepartment of Psychiatry and Clinical Psychology, Faculty of Medicine, Balamand University, Beirut, Lebanon.
A KaramInstitute for Development Research Advocacy and Applied Care (IDRAAC), Beirut, Lebanon.
N KawakamiDepartment of Mental Health, School of Public Health, The University of Tokyo, Tokyo, Japan.
R C KesslerDepartment of Health Care Policy, Harvard Medical School, Boston, Massachusetts, USA.
S LeeDepartment of Psychiatry, Chinese University of Hong Kong, Tai Po, Hong Kong.
J McGrathQueensland Centre for Mental Health Research, The Park Centre for Mental Health, WacolQLD 4072, Australia.ORCID https://orcid.org/0000-0002-4792-6068
B OladejiDepartment of Psychiatry, College of Medicine, University of Ibadan; University College Hospital, Ibadan, Nigeria (Bibiloba).
J Posada-VillaFaculty of Social Sciences, Colegio Mayor de Cundinamarca University, Bogota, Colombia.
D J SteinDepartment of Psychiatry & Mental Health and South African Medical Council Research Unit on Risk and Resilience in Mental Disorders, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa.
Z ZarkovDepartment of Mental Health, National Center of Public Health and Analyses, Sofia, Bulgaria.
P de JongeDepartment of Developmental Psychology, Rijksuniversiteit Groningen, Groningen, Netherlands.
World Mental Health Surveys collaborators
University Medical Center Groningen · NLChinese University of Hong Kong · HKHarvard University · USInstitute for Development, Research, Advocacy and Applied Care · LBNational Center of Public Health and Analyses · BGNational School of Public Health, Management and Professional Development · ROShenzhen KangNing Hospital · CNSouth African Medical Research Council · ZAStony Brook University · USThe University of Queensland · AUThe University of Tokyo · JPUC Davis Health · USUniversidad Colegio Mayor de Cundinamarca · COUniversidade Nova de Lisboa · PTUniversitat Pompeu Fabra · ESUniversity College Hospital, Ibadan · NGUniversity of Al-Qadisiyah · IQUniversity of Balamand · LBUniversity of Ibadan · NGUniversity of Otago · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsIntermittent explosive disorder (IED) is characterised by impulsive anger attacks that vary greatly across individuals in severity and consequence. Understanding IED subtypes has been limited by lack of large, general population datasets including assessment of IED. Using the 17-country World Mental Health surveys dataset, this study examined whether behavioural subtypes of IED are associated with differing patterns of comorbidity, suicidality and functional impairment.

methodsIED was assessed using the Composite International Diagnostic Interview in the World Mental Health surveys (n = 45 266). Five behavioural subtypes were created based on type of anger attack. Logistic regression assessed association of these subtypes with lifetime comorbidity, lifetime suicidality and 12-month functional impairment.

resultsThe lifetime prevalence of IED in all countries was 0.8% (s.e.: 0.0). The two subtypes involving anger attacks that harmed people ('hurt people only' and 'destroy property and hurt people'), collectively comprising 73% of those with IED, were characterised by high rates of externalising comorbid disorders. The remaining three subtypes involving anger attacks that destroyed property only, destroyed property and threatened people, and threatened people only, were characterised by higher rates of internalising than externalising comorbid disorders. Suicidal behaviour did not vary across the five behavioural subtypes but was higher among those with (v. those without) comorbid disorders, and among those who perpetrated more violent assaults.

conclusionsThe most common IED behavioural subtypes in these general population samples are associated with high rates of externalising disorders. This contrasts with the findings from clinical studies of IED, which observe a preponderance of internalising disorder comorbidity. This disparity in findings across population and clinical studies, together with the marked heterogeneity that characterises the diagnostic entity of IED, suggests that it is a disorder that requires much greater research.

Indexed as

Suicidal IdeationAdultAngerComorbidityDisruptive, Impulse Control, and Conduct DisordersFemaleHealth SurveysHumansImpulsive BehaviorMaleMental DisordersSeverity of Illness IndexSuicideViolenceComorbidityimpairmentIntermittent Explosive DisordersuicidalityWorld Mental Health Surveys

Identifiers

PMID32638683
PMCPMC7327434
OpenAlexW3037431053

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.