ArticleEnvironmental science & technology2020
Modeled Impacts of Drinking Water Pb Reduction Scenarios on Children's Exposures and Blood Lead Levels.
Article in Environmental science & technology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 37 citations in OpenAlex.
- Lead Service Lines and Infant Blood Lead Levels.JAMA network open · 2025Article
- Environmental public health research at the U.S. Environmental Protection Agency: A blueprint for exposure science in a connected world.Journal of exposure science & environmental epidemiology · 2025Review
- Heavy Metal Contamination: Sources, Health Impacts, and Sustainable Mitigation Strategies with Insights from Nigerian Case Studies.F1000Research · 2025Review
- Impact of orthophosphate on the solubility and properties of lead orthophosphate nanoparticles.Environmental science : water research & technology · 2024Article
- IEUBK Modeling of Children's Blood Lead Levels in Homes Served by Private Domestic Wells in Three Illinois Counties.International journal of environmental research and public health · 2024Article
- A U.S. Lead Exposure Hotspots Analysis.Environmental science & technology · 2024Article
- Children's lead exposure in the U.S.: Application of a national-scale, probabilistic aggregate model with a focus on residential soil and dust lead (Pb) scenarios.The Science of the total environment · 2023Article
- Extending Regulatory Biokinetic Lead Models towards Food Safety: Evaluation of Consumer Baby Food Contribution to Infant Blood Lead Levels and Variability.Foods (Basel, Switzerland) · 2023Article
- A national survey of lead and other metal(loids) in residential drinking water in the United States.Journal of exposure science & environmental epidemiology · 2023Article
- Lead contamination of public drinking water and academic achievements among children in Massachusetts: a panel study.BMC public health · 2022Article
- Rapid and simple lead service line detection screening protocol using water sampling.AWWA water science · 2021Article
- Lead service line identification: A review of strategies and approaches.AWWA water science · 2021Article
- The urban lead (Pb) burden in humans, animals and the natural environment.Environmental research · 2021Review
- Chronic developmental lead exposure increases μ-opiate receptor levels in the adolescent rat brain.Neurotoxicology · 2021Article
- Variability and sampling of lead (Pb) in drinking water: Assessing potential human exposure depends on the sampling protocol.Environment international · 2021Review
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
In recent years, environmental lead (Pb) exposure through drinking water has resulted in community public health concerns. To understand potential impacts on blood Pb levels (BLLs) from drinking water Pb reduction actions (i.e., combinations of lead service lines [LSL] and corrosion control treatment [CCT] scenarios), EPA's Stochastic Human Exposure and Dose Simulation (SHEDS)-Multimedia/Integrated Exposure Uptake and Biokinetic (IEUBK) model was applied for U.S. children aged 0 to <6 years. The results utilizing a large drinking water sequential sampling data set from 15 cities to estimate model input concentration distributions demonstrated lowest predicted BLLs for the "no LSLs" with "combined CCT" scenario and highest predicted BLLs for the "yes LSLs" and "no CCT" scenario. Modeled contribution to BLLs from ingestion of residential drinking water ranged from ∼10 to 80%, with the highest estimated for formula-fed infants (age 0 to <1 year). Further analysis using a "bounding" data set spanning a range of realistic water Pb concentrations and variabilities showed BLL predictions consistent with the sequential sampling-derived inputs. Our study illustrates (1) effectiveness of LSL replacement coupled with CCT for reducing Pb in drinking water and children's BLLs, and (2) in some age groups, under realistic local and residential water use conditions, drinking water can be the dominant exposure pathway.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.