Evidence map›Paper›PMID 32638529›Full record

ArticleJournal of experimental zoology. Part B, Molecular and developmental evolution2020

Dark world rises: The emergence of cavefish as a model for the study of evolution, development, behavior, and disease.

Suzanne E McGaugh, Johanna E Kowalko, Erik Duboué, Peter Lewis, Tamara A Franz-Odendaal, Nicolas Rohner, Joshua B Gross, Alex C Keene

Abstract read
In one paragraph

Article in Journal of experimental zoology. Part B, Molecular and developmental evolution, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
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  4. Review
  5. Postprandial Sleep in Short-Sleeping Mexican Cavefish.Journal of experimental zoology. Part A, Ecological and integrative physiology · 2024
    Article
  6. Article
  7. Postprandial sleep in short-sleeping Mexican cavefish.bioRxiv : the preprint server for biology · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Suzanne E McGaughEcology, Evolution, and Behavior, University of Minnesota, Saint Paul, Minnesota.ORCID 0000-0003-3163-3436
Johanna E KowalkoThe Jupiter Life Science Initiative and Program in Neurogenetics, Florida Atlantic University, Jupiter, Florida.ORCID 0000-0002-3286-2954
Erik DubouéThe Jupiter Life Science Initiative and Program in Neurogenetics, Florida Atlantic University, Jupiter, Florida.ORCID 0000-0003-3303-5149
Peter LewisThe Jupiter Life Science Initiative and Program in Neurogenetics, Florida Atlantic University, Jupiter, Florida.
Tamara A Franz-OdendaalDepartment of Biology, Mount Saint Vincent University, Halifax, Nova Scotia, Canada.ORCID 0000-0003-4883-2677
Nicolas RohnerStowers Institute for Medical Research, Kansas City, Missouri.ORCID 0000-0003-3248-2772
Joshua B GrossDepartment of Biological Sciences, University of Cincinnati, Cincinnati, Ohio.ORCID 0000-0002-0032-1053
Alex C KeeneThe Jupiter Life Science Initiative and Program in Neurogenetics, Florida Atlantic University, Jupiter, Florida.ORCID 0000-0001-6118-5537

Funding

The developmental and genetic regulators of craniofacial asymmetryR01DE025033 · NIDCR · UNIVERSITY OF CINCINNATI · PI GROSS, JOSHUA BENJAMIN · 2015 to 2019
$2.0M
Understanding complex trait architecture through population genomicsR01GM127872 · NIGMS · UNIVERSITY OF MINNESOTA · PI KEENE, ALEX C, MCGAUGH, SUZANNE · 2018 to 2021
$1.7M
Development of genetic tools for functional analysis of sleep in cavefishR21NS105071 · NINDS · FLORIDA ATLANTIC UNIVERSITY · PI KEENE, ALEX C · 2018 to 2019
$400k
NIDCR NIH HHS R01 DE025033NIGMS NIH HHS R01 GM127872NINDS NIH HHS R21 NS105071
6 · The paper itself

Abstract

A central question in biology is how naturally occurring genetic variation accounts for morphological and behavioral diversity within a species. The Mexican tetra, Astyanax mexicanus, has been studied for nearly a century as a model for investigating trait evolution. In March of 2019, researchers representing laboratories from around the world met at the Sixth Astyanax International Meeting in Santiago de Querétaro, Mexico. The meeting highlighted the expanding applications of cavefish to investigations of diverse aspects of basic biology, including development, evolution, and disease-based applications. A broad range of integrative approaches are being applied in this system, including the application of state-of-the-art functional genetic assays, brain imaging, and genome sequencing. These advances position cavefish as a model organism for addressing fundamental questions about the genetics and evolution underlying the impressive trait diversity among individual populations within this species.

Indexed as

Biological EvolutionCharacidaeModels, AnimalAnimalsBehavior, AnimalCavesDarknessFish Diseases6th Astyanax international meeting, 2019Astyanax mexicanuscavefishmeeting report

Identifiers

PMID32638529
PMCPMC7736471

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.