Evidence map›Paper›PMID 32638509›Full record

ReviewWiley interdisciplinary reviews. RNA2020

The interface between coronaviruses and host cell RNA biology: Novel potential insights for future therapeutic intervention.

David G Maranon, John R Anderson, Abril G Maranon, Jeffrey Wilusz

Open access · bronzeAbstract readReview
In one paragraph

Review in Wiley interdisciplinary reviews. RNA, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Thyroid Dysfunction and COVID-19: The Emerging Role of Selenium in This Intermingled Relationship.International journal of environmental research and public health · 2022
    Review
  10. Article
  11. Review
  12. COVID-19: A methyl-group assault?Medical hypotheses · 2021
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Repurposing Fragile X Drugs to Inhibit SARS-CoV-2 Viral Reproduction.Frontiers in cell and developmental biology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

David G MaranonDepartment of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.
John R AndersonDepartment of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.
Abril G MaranonDepartment of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.
Jeffrey WiluszDepartment of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.ORCID 0000-0001-8535-3435
Colorado State University · US

Funding

Flavivirus non-coding RNAs and the Host mRNA Decay MachineryR01AI123136 · NIAID · COLORADO STATE UNIVERSITY · PI WILUSZ, JEFFREY · 2016 to 2020
$1.9M
NIAID NIH HHS R01 AI123136NIH HHS AI123136
6 · The paper itself

Abstract

Coronaviruses, including SARS-Cov-2, are RNA-based pathogens that interface with a large variety of RNA-related cellular processes during infection. These processes include capping, polyadenylation, localization, RNA stability, translation, and regulation by RNA binding proteins or noncoding RNA effectors. The goal of this article is to provide an in-depth perspective on the current state of knowledge of how various coronaviruses interact with, usurp, and/or avoid aspects of these cellular RNA biology machineries. A thorough understanding of how coronaviruses interact with RNA-related posttranscriptional processes in the cell should allow for new insights into aspects of viral pathogenesis as well as identify new potential avenues for the development of anti-coronaviral therapeutics. This article is categorized under: RNA in Disease and Development > RNA in Disease.

Indexed as

AnimalsBetacoronavirusHost-Pathogen InteractionsHumansMicroRNAsMiddle East Respiratory Syndrome CoronavirusNonsense Mediated mRNA DecayPolyadenylationProtein BiosynthesisRNA, CircularRNA EditingRNA, Long NoncodingRNA, MessengerRNA SplicingRNA StabilityRNA, ViralMicroRNAsRNA, CircularRNA, Long NoncodingRNA, MessengerRNA, ViralcoronavirusmiRNApolyadenylationRNA stabilitytranslation

Identifiers

PMID32638509
PMCPMC7361139
OpenAlexW3041886681

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.