Evidence map›Paper›PMID 32638347›Full record

ArticleJournal of the American Geriatrics Society2020

Recurrence or Relapse of COVID-19 in Older Patients: A Description of Three Cases.

Ludovic Lafaie, Thomas Célarier, Luc Goethals, Bruno Pozzetto, Sylvain Grange, Etienne Ojardias, Cédric Annweiler, Elisabeth Botelho-Nevers

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Journal of the American Geriatrics Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 6 pooled it
1.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 6 syntheses or guidelines pooled it, 74 citations in OpenAlex.

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  6. Is recurrence possible in coronavirus disease 2019 (COVID-19)? Case series and systematic review of literature.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021
    Pooled it
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  18. A case of COVID-19 Reinfection and Systematic Review of Patterns of Reinfection.Infectious diseases in clinical practice (Baltimore, Md.) · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Ludovic LafaieDepartment of Clinical Gerontology, University Hospital of Saint-Etienne, Saint-Etienne, France.
Thomas CélarierDepartment of Clinical Gerontology, University Hospital of Saint-Etienne, Saint-Etienne, France.
Luc GoethalsChaire Santé des Ainés, University of Jean Monnet, Saint-Etienne, France.ORCID https://orcid.org/0000-0001-5809-7966
Bruno PozzettoGroupe Immunité des Muqueuses et Agents Pathogènes-EA3064, University Hospital of Saint-Etienne, Saint-Etienne, France.
Sylvain GrangeDepartment of Radiology, University Hospital of Saint Etienne, Saint-Priest-en-Jarez, France.
Etienne OjardiasDepartment of Clinical Gerontology, University Hospital of Saint-Etienne, Saint-Etienne, France.ORCID https://orcid.org/0000-0003-3413-4341
Cédric AnnweilerDepartment of Geriatric Medicine and Memory Clinic, Research Center on Autonomy and Longevity, University Hospital, Angers, France.ORCID https://orcid.org/0000-0002-7199-8109
Elisabeth Botelho-NeversGroupe Immunité des Muqueuses et Agents Pathogènes-EA3064, University Hospital of Saint-Etienne, Saint-Etienne, France.
Centre Hospitalier Universitaire de Saint-Étienne · FRCancéropôle Lyon Auvergne-Rhône-Alpes · FRInstitute Cancer De La Loire Lucien Neuwirth · FRUniversité Jean Monnet · FRWestern University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCOVID-19 has infected millions of people worldwide, particularly in older adults. The first cases of possible reinfection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were reported in April 2020 among older adults. DESIGN/

settingIn this brief report, we present three geriatric cases with two episodes of SARS-CoV-2 infection separated by a symptom-free interval.

participantsThe participants of this brief report are three cases of hospitalized geriatric women. MEASUREMENTS/

resultsWe note clinical and biological worsening during the second episode of COVID-19 for all three patients. Also, there is a radiological aggravation. The second episode of COVID-19 was fatal in all three cases.

conclusionThis series of three geriatric cases with COVID-19 diagnosed two times apart for several weeks questions the possibility of reinfection with SARS-CoV-2. It raises questions in clinical practice about the value of testing for SARS-CoV-2 infection again in the event of symptomatic reoccurrence. J Am Geriatr Soc 68:2179-2183, 2020.

Indexed as

Aged, 80 and overAnti-Bacterial AgentsAntiviral AgentsBiomarkersCOVID-19COVID-19 Drug TreatmentFatal OutcomeFemaleHumansPandemicsRecurrenceSARS-CoV-2Anti-Bacterial AgentsAntiviral AgentsBiomarkersCOVID-19recurrencesevere acute respiratory syndrome coronavirus 2

Identifiers

PMID32638347
PMCPMC7361461
OpenAlexW3041592048

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.