Evidence map›Paper›PMID 32638141›Full record

ArticleJournal of artificial organs : the official journal of the Japanese Society for Artificial Organs2021

Connector sensors for permittivity-based thrombus monitoring in extracorporeal life support.

Martin W Sifuna, Madoka Koishi, Takuo Uemura, Hanako Tatekawa, Hideaki Haneishi, Achyut Sapkota, Masahiro Takei

Abstract readEvaluation Study
PubMed Publisher
In one paragraph

Article in Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. [Research on a portable electrical impedance tomography system for evaluating blood compatibility of biomaterials].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2025
    Article
  2. Article
  3. Simultaneous electrical online estimation of changes in blood hematocrit and temperature in cardiopulmonary bypass.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Martin W SifunaDivision of Fundamental Engineering, Department of Mechanical Engineering, Graduate School of Science and Engineering, Chiba University, 1-33, Inage-ku, Chiba-shi, Chiba, 263-8522, Japan.
Madoka KoishiDivision of Fundamental Engineering, Department of Mechanical Engineering, Graduate School of Science and Engineering, Chiba University, 1-33, Inage-ku, Chiba-shi, Chiba, 263-8522, Japan.
Takuo UemuraDivision of Fundamental Engineering, Department of Mechanical Engineering, Graduate School of Science and Engineering, Chiba University, 1-33, Inage-ku, Chiba-shi, Chiba, 263-8522, Japan.
Hanako TatekawaDepartment of Medical Engineering, Graduate School of Science and Engineering, Chiba University, Chiba, 263-8522, Japan.
Hideaki HaneishiCenter for Frontier Medical Engineering, Chiba University, Chiba, 263-8522, Japan.
Achyut SapkotaDepartment of Information and Computer Engineering, National Institute of Technology, Kisarazu College, 2-11-1 Kiyomidai-Higashi, Kisarazu, Chiba, 292-0041, Japan. sapkota@j.kisarazu.ac.jp.
Masahiro TakeiDivision of Fundamental Engineering, Department of Mechanical Engineering, Graduate School of Science and Engineering, Chiba University, 1-33, Inage-ku, Chiba-shi, Chiba, 263-8522, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracorporeal circulation is vital in cardiovascular surgery, but thrombus formation at connector interface is a major threat. Optical coherence tomography (OCT) is presently used to monitor thrombogenesis at connectors, but it is expensive to install and complex to use. This study fabricated and evaluated a connector sensor for real-time permittivity-based thrombus monitoring at tube-connector interface. Computational simulations were initially done to pre-evaluate the applicability of connector sensor. The sensor was fabricated by incorporating two stainless steel electrodes on acrylic tube for measuring permittivity changes at the tube-connector interface. OCT images were also taken from the interface at intervals for comparisons. Results show that the sensor was able to detect thrombus formation at the interface in form of sudden rise in permittivity after time t = 9 min. The permittivity changes were confirmed by OCT images which showed thrombus formation after time t = 14 min implying that permittivity changes were due to regional aggregation of red blood cells. The connector sensor is therefore envisioned as an affordable alternative to OCT for real-time permittivity-based monitoring of thrombogenesis at tube-connector interface.

Indexed as

AnimalsExtracorporeal CirculationExtracorporeal Membrane OxygenationThrombosisTomography, Optical CoherenceConnector sensorConnector–tube interfaceExtracorporeal circulationThrombus monitoring

Identifiers

PMID32638141

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.