Evidence map›Paper›PMID 32637937›Full record

ArticleNeuroscience insights2020

Socioeconomic Disadvantage, Chronic Stress, and Hippocampal Subfield Development in Children.

Emily C Merz, Xiaofu He, Brent Myers, Kimberly G Noble

Open access · goldAbstract readComment
In one paragraph

Article in Neuroscience insights, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Emily C MerzDepartment of Psychology, Colorado State University, Fort Collins, CO, USA.ORCID https://orcid.org/0000-0003-1950-2345
Xiaofu HeDepartment of Psychiatry, Columbia University Irving Medical Center and New York State Psychiatric Institute, New York, NY, USA.
Brent MyersDepartment of Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.
Kimberly G NobleDepartment of Biobehavioral Sciences, Teachers College, Columbia University, New York, NY, USA.
Colorado State University · USColumbia University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent findings indicate that hair cortisol concentrations significantly mediate associations between socioeconomic disadvantage and reduced hippocampal CA3 and dentate gyrus volumes in children. In this commentary, we discuss these results and highlight important future research directions, including focusing on hippocampal subfield structural development in relation to episodic memory and mental health; the mechanistic role of excitatory amino acids, such as glutamate; and how chronic stress and cognitive stimulation may make unique proximal contributions to socioeconomic differences in hippocampal subfield volume. Building on the findings in these ways will contribute to advances in strategies aimed at reducing socioeconomic disparities in academic achievement and mental health.

Indexed as

childhood adversitycortisolDentate gyrushippocampusmemory

Identifiers

PMID32637937
PMCPMC7323261
OpenAlexW3037965120

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.