Evidence map›Paper›PMID 32637854›Full record

ArticleACS earth & space chemistry2018

Hydrothermal Decomposition of Amino Acids and Origins of Prebiotic Meteoritic Organic Compounds.

Fabio Pietrucci, José C Aponte, Richard Starr, Andrea Pérez-Villa, Jamie E Elsila, Jason P Dworkin, A Marco Saitta

Open access · greenAbstract read
In one paragraph

Article in ACS earth & space chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Alteration and Stability of Complex Macromolecular Amino Acid Precursors in Hydrothermal Environments.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Fabio PietrucciSorbonne Université, Muséum National d'Histoire Naturelle, UMR CNRS 7590, IRD, Institut de Minéralogie, de Physique des Matériaux et de Cosmochimie, IMPMC, F-75005, Paris, France.
José C AponteThe Goddard Center for Astrobiology and Solar System Exploration Division, Code 691, NASA Goddard Space Flight Center, 8800 Greenbelt Road, Greenbelt, Maryland 20771, United States of America.
Richard StarrThe Goddard Center for Astrobiology and Solar System Exploration Division, Code 691, NASA Goddard Space Flight Center, 8800 Greenbelt Road, Greenbelt, Maryland 20771, United States of America.
Andrea Pérez-VillaSorbonne Université, Muséum National d'Histoire Naturelle, UMR CNRS 7590, IRD, Institut de Minéralogie, de Physique des Matériaux et de Cosmochimie, IMPMC, F-75005, Paris, France.
Jamie E ElsilaThe Goddard Center for Astrobiology and Solar System Exploration Division, Code 691, NASA Goddard Space Flight Center, 8800 Greenbelt Road, Greenbelt, Maryland 20771, United States of America.
Jason P DworkinThe Goddard Center for Astrobiology and Solar System Exploration Division, Code 691, NASA Goddard Space Flight Center, 8800 Greenbelt Road, Greenbelt, Maryland 20771, United States of America.
A Marco SaittaSorbonne Université, Muséum National d'Histoire Naturelle, UMR CNRS 7590, IRD, Institut de Minéralogie, de Physique des Matériaux et de Cosmochimie, IMPMC, F-75005, Paris, France.
Goddard Space Flight Center · USCentre National de la Recherche Scientifique · FR

Funding

Science Planetary Science NASA
6 · The paper itself

Abstract

The organic compounds found in carbonaceous chondrite meteorites provide insight into primordial solar system chemistry. Evaluating the formation and decomposition mechanisms of meteoritic amino acids may aid our understanding of the origins of life and homochirality on Earth. The amino acid glycine is widespread in meteorites and other extraterrestrial environments; other amino acids, such as isovaline, are found with enantiomeric excesses in some meteorites. The relationship between meteoritic amino acids and other compounds with similar molecular structures, such as aliphatic monoamines and monocarboxylic acids is unclear; experimental results evaluating the decomposition of amino acids have produced inconclusive results about the preferred pathways, reaction intermediates, and if the conditions applied may be compatible with those occurring inside meteoritic parent bodies. In this work, we performed extensive tandem metadynamics, umbrella sampling, and committor analysis to simulate the neutral mild hydrothermal decomposition mechanisms of glycine and isovaline and put them into context for the origins of meteoritic organic compounds. Our

Indexed as

ab initio molecular dynamicsenhanced samplingglycineisovalinemeteoritic organicsparent body processes

Identifiers

PMID32637854
PMCPMC7340093
OpenAlexW2798050195

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.