Evidence map›Paper›PMID 32637741›Full record

ArticleBioactive materials2020

Biofilm-inspired adhesive and antibacterial hydrogel with tough tissue integration performance for sealing hemostasis and wound healing.

Wei Han, Bo Zhou, Kai Yang, Xin Xiong, Shifang Luan, Yu Wang, Zheng Xu, Peng Lei, Zhengshan Luo, Jian Gao and 6 more

Open access · goldAbstract read
In one paragraph

Article in Bioactive materials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
24.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 204 citations in OpenAlex.

  1. Article
  2. Article
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  4. Review
  5. [Research advances in three-dimensional bioprinted wound dressings].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025
    Review
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  19. Review
  20. RapidlyMaterials today. Bio · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 2 countries.

Wei HanState Key Laboratory of Materials-Oriented Chemical Engineering, College of Food Science and Light Industry, Nanjing Tech University, Nanjing, 211816, PR China.
Bo ZhouDepartment of Gastrointestinal Surgery, Department of General Surgery, The First Affiliated Hospital of Anhui Medical University, 218 JiXi Avenue, Hefei, 230022, Anhui, PR China.
Kai YangState Key Laboratory of Materials-Oriented Chemical Engineering, College of Food Science and Light Industry, Nanjing Tech University, Nanjing, 211816, PR China.
Xin XiongNatural and Medical Sciences Institute at the University of Tübingen, Markwiesenstr. 55, 72770, Reutlingen, Germany.
Shifang LuanState Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, PR China.
Yu WangState Key Laboratory of Materials-Oriented Chemical Engineering, College of Food Science and Light Industry, Nanjing Tech University, Nanjing, 211816, PR China.
Zheng XuState Key Laboratory of Materials-Oriented Chemical Engineering, College of Food Science and Light Industry, Nanjing Tech University, Nanjing, 211816, PR China.
Peng LeiState Key Laboratory of Materials-Oriented Chemical Engineering, College of Food Science and Light Industry, Nanjing Tech University, Nanjing, 211816, PR China.
Zhengshan LuoState Key Laboratory of Materials-Oriented Chemical Engineering, College of Food Science and Light Industry, Nanjing Tech University, Nanjing, 211816, PR China.
Jian GaoSchool of Marine and Bioengineering, Yancheng Institute of Technology, Yancheng, 224051, PR China.
Yijing ZhanState Key Laboratory of Materials-Oriented Chemical Engineering, College of Food Science and Light Industry, Nanjing Tech University, Nanjing, 211816, PR China.
Guopu ChenDepartment of Comparative Medicine, Jinling Hospital, No. 305 Zhongshan East Road, Nanjing, 210002, PR China.
Lei LiangDepartment of Comparative Medicine, Jinling Hospital, No. 305 Zhongshan East Road, Nanjing, 210002, PR China.
Rui WangState Key Laboratory of Materials-Oriented Chemical Engineering, College of Food Science and Light Industry, Nanjing Tech University, Nanjing, 211816, PR China.
Sha LiState Key Laboratory of Materials-Oriented Chemical Engineering, College of Food Science and Light Industry, Nanjing Tech University, Nanjing, 211816, PR China.
Hong XuState Key Laboratory of Materials-Oriented Chemical Engineering, College of Food Science and Light Industry, Nanjing Tech University, Nanjing, 211816, PR China.
Nanjing Tech University · CNNanjing General Hospital of Nanjing Military Command · CNAnhui Medical University · CNChinese Academy of Sciences · CNNatural and Medical Sciences Institute · DEYancheng Institute of Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Uncontrolled bleeding and infection can cause significant increases in mortalities. Hydrogel sealants have attracted extensive attention for their ability to control bleeding. However, because interfacial water is a formidable barrier to strong surface bonding, a challenge remains in finding a product that offers robust tissue adhesion combined with anti-infection properties. Inspired by the strong adhesive mechanism of biofilm and mussels, we report a novel dual bionic adhesive hydrogel (DBAH) based on chitosan grafted with methacrylate (CS-MA), dopamine (DA), and N-hydroxymethyl acrylamide (NMA) via a facile radical polymerization process. CS-MA and DA were simultaneously included in the adhesive polymer for imitating the two key adhesive components: polysaccharide intercellular adhesin (PIA) of

Indexed as

AdhesiveAntibacterialBiofilmDual-biomimeticHemostasisHydrogelMussel

Identifiers

PMID32637741
PMCPMC7317234
OpenAlexW3036424386

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.