Evidence map›Paper›PMID 32637740›Full record

ArticleBioactive materials2020

Gadolinium-hyaluronic acid nanoparticles as an efficient and safe magnetic resonance imaging contrast agent for articular cartilage injury detection.

Rong Lu, Yuyang Zhang, Hongyue Tao, Lu Zhou, Huidi Li, Tianwu Chen, Peng Zhang, Yao Lu, Shuang Chen

Open access · goldAbstract read
In one paragraph

Article in Bioactive materials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 45 citations in OpenAlex.

  1. Review
  2. Contrast Agents for Enhanced Bioimaging: A Comprehensive Review.Chembiochem : a European journal of chemical biology · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Targeted editing of CCL5 with CRISPR-Cas9 nanoparticles enhances breast cancer immunotherapy.Apoptosis : an international journal on programmed cell death · 2025
    Article
  7. A novel MRI contrast agent NaGdFScientific reports · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Synthesis and characterization of GdScientific reports · 2023
    Article
  15. Article
  16. Article
  17. Hope for bone regeneration: The versatility of iron oxide nanoparticles.Frontiers in bioengineering and biotechnology · 2022
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Rong LuDepartment of Radiology, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Yuyang ZhangDepartment of Radiology, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Hongyue TaoDepartment of Radiology, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Lu ZhouDepartment of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai, 201203, China.
Huidi LiDepartment of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai, 201203, China.
Tianwu ChenDepartment of Sports Medicine, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Peng ZhangDepartment of Sports Medicine, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Yao LuGuangdong Key Lab of Orthopedic Technology and Implant Materials, Key Laboratory of Trauma & Tissue Repair of Tropical Area of PLA, Guangzhou, Guangdong, 510010, China.
Shuang ChenDepartment of Radiology, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Fudan University · CNKey Laboratory of Guangdong Province · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accurate detection of cartilage injuries is critical for their proper treatment because these injuries lack the self-healing ability and lead to joint dysfunction. However, the low longitudinal T1 relaxivity (

Indexed as

Cartilage injuryGadoliniumHyaluronic acidMagnetic resonance imaging contrast agentsNanoparticles

Identifiers

PMID32637740
PMCPMC7317168
OpenAlexW3036296611

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.