ArticleContemporary clinical trials communications2020
A randomized controlled trial comparing intensive non-surgical treatment with bariatric surgery in adolescents aged 13-16 years (AMOS2): Rationale, study design, and patient recruitment.
Article in Contemporary clinical trials communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT02378259 (AMOS2), which is not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
AMOS2 (Adolescent Morbid Obesity Surgery)
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Surgery for the treatment of obesity in children and adolescents.The Cochrane database of systematic reviews · 2022Pooled it
- Motivators and Barriers to Seeking Metabolic and Bariatric Surgery Among Adolescents: A Qualitative Study.Obesity science & practice · 2025Article
- Cognitive functioning in adolescents with severe obesity undergoing bariatric surgery or intensive non-surgical treatment in Sweden (AMOS2): a multicentre, open-label, randomised controlled trial.EClinicalMedicine · 2024Article
- Characteristics of adolescents referred for bariatric surgery in Abu Dhabi, United Arab Emirates.Frontiers in pediatrics · 2024Article
- Long-term Outcomes Following Adolescent Metabolic and Bariatric Surgery.The Journal of clinical endocrinology and metabolism · 2023Review
- The impact of parental bariatric surgery and patient age on laparoscopic sleeve gastrectomy outcomes in adolescents.Surgical endoscopy · 2022Article
- Article
- Role of bile acids in overweight and obese children and adolescents.Frontiers in endocrinology · 2022Review
- Adapting pediatric obesity care to better suit adolescent patients: Design of a treatment platform and results compared with standard care in the national patient quality register.Obesity science & practice · 2021Article
- High prevalence of neurodevelopmental problems in adolescents eligible for bariatric surgery for severe obesity.Acta paediatrica (Oslo, Norway : 1992) · 2021Article
- Outcomes of Bariatric Surgery in Older Versus Younger Adolescents.Pediatrics · 2021Observational
Corrections and comments
- Erratum issued
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrevious non-randomized studies show similar outcomes in adolescents and adults after bariatric surgery. We describe the study protocol, recruitment, and selected baseline data of patients in a randomized multi-center study, the Adolescent Morbid Obesity Surgery 2 (AMOS2).
methodsThree clinics in Sweden collaborated in designing the study and recruitment of patients from August 1, 2014 to June 30, 2017. Patients were selected among adolescents 13-16 years of age attending third-level obesity care for at least one year. Patients were randomized 1:1 to bariatric surgery (predominantly Roux-en-Y gastric bypass) or intensive non-surgical treatment starting with an eight-week low-calorie-diet.
resultsFifty adolescents (37 girls) were randomized, 25 (19 girls) to bariatric surgery. Mean age was 15.7 years (range 13.3-16.9), weight 122.6 kg (range 95-183.3), Body Mass Index (BMI) 42.6 kg/m
conclusionsThis clinical trial, randomizing adolescents with severe obesity to bariatric surgery or intensive non-surgical treatment, aims at informing about whether it is beneficial to undergo bariatric surgery in early adolescence. It will also enlighten the outcome of comprehensive non-surgical treatment. The study was registered at www.clinicalTrials.gov number NCT02378259.
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