Evidence map›Paper›PMID 32637668›Full record

ArticleSynthetic and systems biotechnology2020

Silk fibroin as an additive for cell-free protein synthesis.

Marilyn S Lee, Chia-Suei Hung, Daniel A Phillips, Chelsea C Buck, Maneesh K Gupta, Matthew W Lux

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Synthetic and systems biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Multiscale design of cell-free biologically active architectural structures.Frontiers in bioengineering and biotechnology · 2023
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Marilyn S LeeUS Army Combat Capabilities Development Command Chemical and Biological Center, 8567 Ricketts Point Road, Aberdeen Proving Ground, MD, 21010, USA.
Chia-Suei HungUS Air Force Research Laboratory, 2179 12th St., B652/R122 Wright-Patterson Air Force Base, OH, 45433, USA.
Daniel A PhillipsUS Naval Research Laboratory Center for Bio/Molecular Science and Engineering, Bldg. 42, Room 303 4555 Overlook Ave. Washington, DC 20375, UES Inc., 4401 Dayton Xenia Rd., Beavercreek, OH 45432, USA.
Chelsea C BuckUS Air Force Research Laboratory, 2179 12th St., B652/R122 Wright-Patterson Air Force Base, OH, 45433, USA.
Maneesh K GuptaUS Air Force Research Laboratory, 2179 12th St., B652/R122 Wright-Patterson Air Force Base, OH, 45433, USA.
Matthew W LuxUS Army Combat Capabilities Development Command Chemical and Biological Center, 8567 Ricketts Point Road, Aberdeen Proving Ground, MD, 21010, USA.
United States Army Combat Capabilities Development Command · USUnited States Naval Research Laboratory · USWright-Patterson Air Force Base · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell-free systems contain many proteins and metabolites required for complex functions such as transcription and translation or multi-step metabolic conversions. Research into expanding the delivery of these systems by drying or by embedding into other materials is enabling new applications in sensing, point-of-need manufacturing, and responsive materials. Meanwhile, silk fibroin from the silk worm,

Indexed as

Cell-free protein synthesisCell-free systemsCFPSCFPS, Cell-free Protein SynthesisHRP, horse radish peroxidasePreservationSEM, Scanning Electron MicroscopysfGFP, superfolder green fluorescent proteinSF, Silk FibroinSilk fibroin

Identifiers

PMID32637668
PMCPMC7320238
OpenAlexW3037455377

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.