Evidence map›Paper›PMID 32637653›Full record

ArticleEuropean stroke journal2020

SiPP (Stroke in Pregnancy and Postpartum): A prospective, observational, international, multicentre study on pathophysiological mechanisms, clinical profile, management and outcome of cerebrovascular diseases in pregnant and postpartum women.

Svetlana Lorenzano, Christine Kremer, Aleksandra Pavlovic, Dejana R Jovanovic, Else Charlotte Sandset, Hanne Christensen, Cheryl Bushnell, Anita Arsovska, Nikola Sprigg, Christine Roffe and 25 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European stroke journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Sex and gender-related differences in neurological diseases: current challenges and recommendations for clinical practice.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors at 20 institutions in 19 countries.

Svetlana LorenzanoDepartment of Human Neurosciences, Sapienza University of Rome, Rome, Italy.ORCID https://orcid.org/0000-0002-7100-1778
Christine KremerNeurology Department, Skåne University Hospital, Malmö, Sweden.
Aleksandra PavlovicNeurology Clinic, Clinical Center of Serbia, Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
Dejana R JovanovicNeurology Clinic, Clinical Center of Serbia, Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
Else Charlotte SandsetDepartment of Neurology, Oslo University Hospital, Oslo, Norway.
Hanne ChristensenBispebjerg Hospital, Copenhagen University, Copenhagen, Denmark.
Cheryl BushnellWake Forest Baptist Health, Medical Center Boulevard, Winston Salem, NC, USA.
Anita ArsovskaUniversity Clinic of Neurology, Medical Faculty, University 'Ss Cyril and Methodius', Skopje, Republic of North Macedonia.
Nikola SpriggNottingham University Hospitals NHS Trust, University of Nottingham, Nottingham, UK.
Christine RoffeInstitute for Science and Technology in Medicine, Keele University, c/o Guy Hilton Research Centre, Keele, UK.
Petra IjäsDepartment of Neurology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.
Zuzana GdovinovaDepartment of Neurology, Pavol Jozef Safarik University, Košice, Slovak Republic.
Anne AlexandrovDepartment of Neurology, College of Nursing and College of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
Marialuisa ZeddeNeurology and Stroke Units, Azienda Unità Sanitaria Locale, IRCCS Reggio Emilia, Italy.
Rossana TassiStroke Unit, Azienda Ospedaliera Universitaria Senese, Siena, Italy.
Monica AcciaresiMedicina Interna Vascolare - Stroke Unit, Ospedale Santa Maria della Misericordia, University of Perugia, Perugia, Italy.
Maria LantzNeurology Department, Karolinska Institutet, Stockholm, Sweden.
Katharina SunnerhagenDepartment of Neurology and Rehabilitation, Sahlgrenska University Hospital, Gothenburg, Sweden.ORCID https://orcid.org/0000-0002-5940-4400
Marija ZarkovClinical Center of Vojvodina, Clinic of Neurology, Novi Sad, Serbia.
Kirsi RantanenDepartment of Neurology, University of Helsinki, Helsinki, Finland.
Fabienne PerrenNeuroscience Center, University of Geneva, Geneva, Switzerland.
Helle K IversenStroke Centre Rigshospitalet, Department of Neurology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Christina KruuseDepartment of Neurology and Neurovascular Research Unit, Herlev Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
Agnieszka SlowikDepartment of Neurology, Jagiellonian University, Krakow, Poland.
Paola PalazzoDepartment of Neurology, Poitiers University Hospital and University of Poitiers, Poitiers, France.
Janika KorvDepartment of Neurology and Neurosurgery, University of Tartu, Tartu, Estonia.
Annette FrommDepartment of Neurology, Haukeland University Hospital, Bergen, Norway.
Arijana Lovrencic-HuzjanDepartment of Neurology, Sestre Milosrdnice UHC, Zagreb, Croatia.
Eleni KorompokiDivision of Brain Sciences, Imperial College London, London, UK.
Ana Catarina FonsecaDepartment of Neurosciences (Neurology), Hospital de Santa Maria, University of Lisbon, Lisbon, Portugal.
Seana L GallMenzies Institute for Medical Research Tasmania, University of Tasmania, Hobart, Australia.
Freimuth BrunnerDepartment of Neurology, Klinikum Bremen-Mitte, Bremen, Germany.ORCID https://orcid.org/0000-0002-2818-2665
Valeria CasoStroke Unit, Ospedale Santa Maria della Misericordia, University of Perugia, Perugia, Italy.
Simona SaccoDepartment of Clinical Sciences and Biotechnology, University of L'Aquila, L'Aquila, Italy.
SiPP Trial Investigators and ESO-WISE Group
University of Belgrade · RSUniversity of Copenhagen · DKUniversity of Helsinki · FIUniversity of Perugia · ITAtrium Health Wake Forest Baptist · USAzienda Ospedaliera Universitaria Senese · ITAzienda Sanitaria Unità Locale di Reggio Emilia · ITBispebjerg Hospital · DKHaukeland University Hospital · NOJagiellonian University · PLKarolinska Institutet · SEKeele University · GBKlinički centar Vojvodine · RSKlinikum Bremen-Mitte · DELund University · SENational and Kapodistrian University of Athens · GRNottingham University Hospitals NHS Trust · GBOslo University Hospital · NOSahlgrenska University Hospital · SESapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

rationaleCerebrovascular diseases associated with pregnancy and postpartum period are uncommon; however, they can have an important impact on health of both women and foetus or newborn.

aimsTo evaluate the frequency, characteristics and management of cerebrovascular events in pregnant/postpartum women, to clarify pathophysiological mechanisms underlying the occurrence of these events including biomolecular aspects, and to assess the short- and long-term cerebrovascular and global cardiovascular outcome of these patients, their predictors and infant outcome. METHODS AND

designThis is an observational, prospective, multicentre, international case-control study. The study will include patients with cerebrovascular events during pregnancy and/or within six months after delivery. For each included case, two controls will be prospectively recruited: one pregnant or puerperal subject without any history of cerebrovascular event and one non-pregnant or non-puerperal subject with a recent cerebrovascular event. All controls will be matched by age, ethnicity and type of cerebrovascular event with their assigned cases. The pregnant controls will be matched also by pregnancy weeks/trimester. Follow-up will last 24 months for the mother and 12 months for the infant. SUMMARY: To better understand causes and outcomes of uncommon conditions like pregnancy/postpartum-related cerebrovascular events, the development of multisite, multidisciplinary registry-based studies, such as the Stroke in Pregnancy and Postpartum study, is needed in order to collect an adequate number of patients, draw reliable conclusions and give definite recommendations on their management.

Indexed as

cerebrovascular diseaseoutcomepostpartumpregnancypuerperiumStroke

Identifiers

PMID32637653
PMCPMC7313370
OpenAlexW2993219060

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.