ArticleScience advances2020
Single yeast cell nanomotions correlate with cellular activity.
Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- YOLO with Kolmogorov-Arnold networks and vision-language foundation models for interpretable object detection with trustworthy multimodal AI in computer vision perception.Scientific reports · 2026Article
- Rapid Optical Nanomotion-Based Antibiotic Susceptibility Testing of Kombucha-Associated Acetic Acid Bacteria andFoods (Basel, Switzerland) · 2026Article
- Single-cell vibration analysis for potential diagnostic applications.Biophysical reports · 2026Article
- Rotating Gold Nanomotors for High-Resolution Mapping of Subcellular Nanomotions.Small methods · 2025Article
- Real-time evaluation of macozinone activity againstAntimicrobial agents and chemotherapy · 2025Article
- Rapid Detection ofBiomedicines · 2024Article
- Optical Nanomotion Detection to Rapidly Discriminate between Fungicidal and Fungistatic Effects of Antifungals on Single-CellAntibiotics (Basel, Switzerland) · 2024Article
- Accurate and rapid antibiotic susceptibility testing using a machine learning-assisted nanomotion technology platform.Nature communications · 2024Article
- An Optical Fiber-Based Nanomotion Sensor for Rapid Antibiotic and Antifungal Susceptibility Tests.Nano letters · 2024Article
- A simplified version of rapid susceptibility testing of bacteria and yeasts using optical nanomotion detection.Frontiers in microbiology · 2024Article
- Article
- The Hypothesis of a "Living Pulse" in Cells.Life (Basel, Switzerland) · 2023Article
- Simple optical nanomotion method for single-bacterium viability and antibiotic response testing.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Modulation of the nanoscale motion rate ofFrontiers in microbiology · 2023Article
- Mitochondrial nanomotion measured by optical microscopy.Frontiers in microbiology · 2023Article
- Super-resolution optical microscopy using cylindrical vector beams.Nanophotonics (Berlin, Germany) · 2022Review
- Measurement of the low-frequency charge noise of bacteria.Physical review. E · 2022Article
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Living single yeast cells show a specific cellular motion at the nanometer scale with a magnitude that is proportional to the cellular activity of the cell. We characterized this cellular nanomotion pattern of nonattached single yeast cells using classical optical microscopy. The distribution of the cellular displacements over a short time period is distinct from random motion. The range and shape of such nanomotion displacement distributions change substantially according to the metabolic state of the cell. The analysis of the nanomotion frequency pattern demonstrated that single living yeast cells oscillate at relatively low frequencies of around 2 hertz. The simplicity of the technique should open the way to numerous applications among which antifungal susceptibility tests seem the most straightforward.
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