Evidence map›Paper›PMID 32637558›Full record

ArticleAddictive behaviors reports2020

Common Elements Treatment Approach (CETA) for unhealthy alcohol use among persons with HIV in Zambia: Study protocol of the ZCAP randomized controlled trial.

Jeremy C Kane, Anjali Sharma, Laura K Murray, Geetanjali Chander, Tukiya Kanguya, Molly E Lasater, Stephanie Skavenski, Ravi Paul, John Mayeya, Carla Kmett Danielson and 3 more

Registry-linked trialAbstract read
In one paragraph

Article in Addictive behaviors reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03966885 (Zambia Common Elements Treatment Approach Pilot Study), which is not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03966885 naterminatednot on this map

Zambia Common Elements Treatment Approach Pilot Study

TypeinterventionalSponsorColumbia UniversityRan2019 to 2020Enrolled160ConditionsAlcohol Use Disorder, Depression, Post-traumatic Stress Disorder, HIV/AIDSArmsBrief Intervention, Common Elements Treatment Approach (CETA)
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jeremy C KaneColumbia University Mailman School of Public Health, New York, NY, USA.
Anjali SharmaCentre for Infectious Disease Research in Zambia, Lusaka, Zambia.
Laura K MurrayJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Geetanjali ChanderJohns Hopkins University School of Medicine, Baltimore, MD, USA.
Tukiya KanguyaCentre for Infectious Disease Research in Zambia, Lusaka, Zambia.
Molly E LasaterJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Stephanie SkavenskiJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Ravi PaulUniversity of Zambia, School of Medicine, University Teaching Hospital, Lusaka, Zambia.
John MayeyaZambia Ministry of Health, Lusaka, Zambia.
Carla Kmett DanielsonMedical University of South Carolina, Charleston, SC, USA.
Jenala ChipunguCentre for Infectious Disease Research in Zambia, Lusaka, Zambia.
Chipo ChitambiCentre for Infectious Disease Research in Zambia, Lusaka, Zambia.
Michael J VinikoorUniversity of Alabama at Birmingham School of Medicine, Birmingham, AL, USA.

Funding

Mentoring and Patient Oriented Research at the Nexus of Unhealthy Alcohol Use and HIVK24AA027483 · NIAAA · UNIVERSITY OF WASHINGTON · PI GEETANJALI CHANDER · 2019 to 2026
$1.3M
FEASIBILITY AND PRELIMINARY EFFECTIVENESS OF A TRANSDIAGNOSTIC COGNITIVE BEHAVIORAL THERAPY TREATMENT APPROACH FOR ALCOHOL MISUSE INTEGRATED WITHIN HIV CARE IN ZAMBIAR34AA027200 · NIAAA · JOHNS HOPKINS UNIVERSITY · PI KANE, JEREMY CALVIN, VINIKOOR, MICHAEL JEFFREY · 2018 to 2020
$585k
NIAAA NIH HHS K24 AA027483NIAAA NIH HHS R34 AA027200
6 · The paper itself

Abstract

aimsPrevalence of unhealthy alcohol use and co-occurring mental health problems is high among persons living with HIV (PLWH) in sub-Saharan Africa (SSA). Yet, there is a dearth of evidence-based treatment options that can address both unhealthy alcohol use and comorbidities in SSA HIV care settings. Recent studies testing single-session alcohol brief interventions (BIs) among PLWH in SSA have suggested that more robust treatments are needed. This paper describes the protocol of a pilot randomized controlled superiority trial that will test the effectiveness of an evidence-based transdiagnostic multi-session psychotherapy, the Common Elements Treatment Approach (CETA), compared to a control condition consisting of a single session brief alcohol intervention (BI) based on CETA, at reducing unhealthy alcohol use, mental health problems, and other substance use among PLWH in urban Zambia.

methodsThe study is a single-blind, parallel, individually randomized trial conducted in HIV treatment centers in Lusaka. 160 PLWH who meet criteria for unhealthy alcohol use + mental health or substance use comorbidities and/or have a more severe alcohol use disorder are eligible. Participants are randomized 1:1 to receive the single-session BI or CETA. Outcomes are assessed at baseline and a six-month follow-up and include unhealthy alcohol use, depression, trauma symptoms, and other substance use.

conclusionsThe trial is a first step in establishing the effectiveness of CETA at reducing unhealthy alcohol use and comorbidities among PLWH in SSA. If effectiveness is demonstrated, a larger trial featuring long-term follow-ups and HIV treatment outcomes will be undertaken.

Indexed as

Brief interventionHIVRandomized controlled trialSubstance useTransdiagnostic therapyUnhealthy alcohol useZambia

Identifiers

PMID32637558
PMCPMC7330869

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.