ArticleArthroplasty today2020
Survivorship of Megaprostheses in Revision Hip and Knee Arthroplasty for Septic and Aseptic Indications: A Retrospective, Multicenter Study With Minimum 2-Year Follow-Up.
Article in Arthroplasty today, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Proximal femoral replacement for non-neoplastic conditions: a systematic review on current outcomes.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2022Pooled it
- Limb salvage in multiple revision total knee arthroplasty using customised implants: When sleeves and cones are no longer an option.Journal of experimental orthopaedics · 2026Article
- Periprosthetic joint infection of megaprostheses for oncologic and non-oncologic indications-IMPLANT retention or removal? A retrospective cohort study of 50 cases.Arthroplasty (London, England) · 2025Article
- Characteristics and Epidemiology of Megaprostheses Infections: A Systematic Review.Healthcare (Basel, Switzerland) · 2024Review
- Fast Track Protocols and Early Rehabilitation after Surgery in Total Hip Arthroplasty: A Narrative Review.Clinics and practice · 2023Review
- Rotating Hinge Distal Femur Replacement: A Turn for the Worse.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2022Article
- Different outcomes after proximal femoral replacement in oncologic and failed revision arthroplasty patients - a retrospective cohort study.BMC musculoskeletal disorders · 2021Article
- Individual Revision Knee Arthroplasty Is a Safe Limb Salvage Procedure.Journal of personalized medicine · 2021Article
Corrections and comments
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Authors and funding
12 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe use of megaprostheses in nononcologic patients has been associated with complication rates greater than 50%. In patients with prior periprosthetic joint infection (PJI) with subsequent two-stage reimplantation, this complication rate may be even higher. This study was to investigate the outcomes of megaprostheses in nononcologic patients undergoing revision hip/knee arthroplasty.
methodsWe retrospectively studied patients who underwent megaprosthesis replacements from 1999 to 2017 at 5 hospitals with minimum 24 months of follow-up. Patients were stratified based on history of prior PJI (septic vs aseptic) and location of the megaprosthesis (the hip or knee). Postoperative complications were classified as soft-tissue failure, aseptic loosening, structural failure, and infection.
resultsOf the 42 patients, 19 were in the septic cohort and 23 were in the aseptic cohort. The overall complication rate was 28.6%. Complication rates for the septic and aseptic cohorts were 32% and 26%, respectively (
conclusionsThere is no difference in the postoperative complication rates between the septic or aseptic cohorts undergoing revision hip or knee megaprosthesis replacements. In patients with prior PJI, proximal femoral replacements have improved short-term survivorship compared with distal femoral or proximal tibial replacements.
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