Evidence map›Paper›PMID 32637465›Full record

ArticleEuropean journal of radiology open2020

Developing a lung nodule management protocol specifically for cardiac CT: Methodology in the DISCHARGE trial.

Robert Haase, Jonathan D Dodd, Hans-Ulrich Kauczor, Ella A Kazerooni, Marc Dewey

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of radiology open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02400229 (Diagnostic Imaging Strategies for Patients With Stable Chest Pain and Intermediate Risk of Coronary Artery Disease), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02400229 nacompletednot on this map

Diagnostic Imaging Strategies for Patients With Stable Chest Pain and Intermediate Risk of Coronary Artery Disease: Comparative Effectiveness Research of Existing Technologies) - A Pragmatic Randomised Controlled Trial of CT Versus ICA

TypeinterventionalSponsorCharite University, Berlin, GermanyRan2015 to 2022Enrolled3,546ConditionsCoronary Artery DiseaseArmsComputed tomography angiography (cardiac CT), Invasive coronary angiography (ICA)
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Robert HaaseDepartment of Radiology, Charité University Hospital, Chariteplatz 1, 10117, Berlin, Germany.
Jonathan D DoddDepartment of Radiology, St. Vincent's University Hospital, Elm Park, Dublin 4, Ireland.
Hans-Ulrich KauczorDepartment of Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany.
Ella A KazerooniMichigan Medicine - University of Michigan Medical School, Departments of Radiology & Internal Medicine, 1500 E. Medical Center Dr, RM 5482 Ann Arbor, MI, 48109, United States.
Marc DeweyDepartment of Radiology, Charité University Hospital, Chariteplatz 1, 10117, Berlin, Germany.
Charité - Universitätsmedizin Berlin · DEHeidelberg University · DEMichigan Medicine · USSt. Vincent's University Hospital · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIn this methodology paper we describe the development of a lung nodule management algorithm specifically for patients undergoing cardiac CT.

methodsWe modified the Lung-RADS algorithm specifically to manage lung nodules incidentally detected on cardiac CT (Lung-RADS for cardiac CT). We will evaluate the modified algorithm as part of the DISCHARGE trial (www.dischargetrial.eu) in which patients with suspected coronary artery disease are randomly assigned to cardiac CT or invasive coronary angiography across Europe at 16 sites involving 3546 patients. Patients will be followed for up to four years.

resultsThe major adjustments to Lung-RADS specifically for cardiac CT relate to 1) incomplete coverage of the lungs by cardiac CT compared with chest CT, and when to order a completion chest CT versus a follow up chest CT, 2) cardiac CT findings will not trigger annual lung-cancer screening, and 3) a lower threshold of at least 10 mm for classifying new ground glass nodules as probably benign (category 3).

conclusionsThe DISCHARGE trial will assess a lung nodule management algorithm designed specifically for cardiac CT in patients with stable chest pain across Europe.

Indexed as

ACR, American College of RadiologyAdultComputed tomography angiography*eCRF, electronic clinical report formIncidental findings*LDCT, low-dose computed tomographyLung/diagnostic imagingNLST, national lung cancer screening trial

Identifiers

PMID32637465
PMCPMC7327416
OpenAlexW3037473662

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.