Evidence map›Paper›PMID 32637297›Full record

ArticleNanotheranostics2020

Brain iron deposition after Ferumoxytol-enhanced MRI: A study of Porcine Brains.

Ashok Joseph Theruvath, Maryam Aghighi, Michael Iv, Hossein Nejadnik, Jonathan Lavezo, Laura Jean Pisani, Heike Elisabeth Daldrup-Link

Open access · goldAbstract read
In one paragraph

Article in Nanotheranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.4field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Safety and TJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Ashok Joseph TheruvathDepartment of Radiology, Molecular Imaging Program at Stanford, Stanford University, CA, USA.
Maryam AghighiDepartment of Radiology, Molecular Imaging Program at Stanford, Stanford University, CA, USA.
Michael IvDepartment of Radiology, Molecular Imaging Program at Stanford, Stanford University, CA, USA.
Hossein NejadnikDepartment of Radiology, Molecular Imaging Program at Stanford, Stanford University, CA, USA.
Jonathan LavezoDepartment of Pathology, School of Medicine, Stanford University, Stanford, CA, USA.
Laura Jean PisaniDepartment of Radiology, Molecular Imaging Program at Stanford, Stanford University, CA, USA.
Heike Elisabeth Daldrup-LinkDepartment of Radiology, Molecular Imaging Program at Stanford, Stanford University, CA, USA.
Stanford University · USUniversity Medical Center of the Johannes Gutenberg University Mainz · DE

Funding

Monitoring of Stem Cell Engraftment in Arthritic Joints with MR ImagingR01AR054458 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DALDRUP-LINK, HEIKE ELIZABETH · 2008 to 2021
$6.7M
NIAMS NIH HHS R01 AR054458
6 · The paper itself

Abstract

Recent evidence of gadolinium deposition in the brain has raised safety concerns. Iron oxide nanoparticles are re-emerging as promising alternative MR contrast agents, because the iron core can be metabolized. However, long-term follow up studies of the brain after intravenous iron oxide administration have not been reported thus far. In this study, we investigated, if intravenously administered ferumoxytol nanoparticles are deposited in porcine brains.

Indexed as

BrainMagnetic Resonance ImagingMagnetite NanoparticlesAdministration, IntravenousAnimalsBrain ChemistryCase-Control StudiesContrast MediaFerrosoferric OxideProspective StudiesSwineSwine, MiniatureTissue DistributionContrast MediaFerrosoferric OxideMagnetite Nanoparticlesbrain depositioniron oxide nanoparticleMRI

Identifiers

PMID32637297
PMCPMC7332795
OpenAlexW3038540922

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.