ReviewFrontiers in endocrinology2020
Consequences of Severe Iodine Deficiency in Pregnancy: Evidence in Humans.
Review in Frontiers in endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.
- Prevalence of insufficient iodine intake in pregnancy worldwide: a systematic review and meta-analysis.European journal of clinical nutrition · 2022Pooled it
- The relationship between different iodine sources and nutrition in pregnant women and adults.Frontiers in endocrinology · 2022Trial
- Optimisation of Micronutrient Supplementation During Pregnancy: Interactions Between Bioactive Compounds, Their Impact on Health, and Regulatory Considerations.Biomolecules · 2026Review
- Stage-specific variations in urinary and salt iodine among pregnant women in Beijing.Frontiers in nutrition · 2026Article
- Beyond Calories: Addressing Micronutrient Deficiencies in the World's Most Vulnerable Communities-A Review.Nutrients · 2025Review
- Reaffirming the role of iodine in cognitive health: a call for lifespan-based public health action.Annals of medicine and surgery (2012) · 2025Article
- Investigating Birth and Thyroid Outcomes of Maternal-Fetal Environmental Exposures (IBM-E): A Cohort Protocol for Dietary Iodine and Endocrine Disruptors.Endocrinology and metabolism (Seoul, Korea) · 2025Observational
- Should iodine supplementation be universally recommended for pregnant women in Brazil? A position statement from the Thyroid Department of the Brazilian Society of Endocrinology and Metabolism (SBEM).Archives of endocrinology and metabolism · 2025Review
- 50 YEARS OF NEWBORN SCREENING FOR CONGENITAL HYPOTHYROIDISM: EVOLUTION OF INSIGHTS IN ETIOLOGY, DIAGNOSIS AND MANAGEMENT: Management during pregnancy and long-term outcomes of adult patients with congenital hypothyroidism.European thyroid journal · 2025Review
- Effect of Iodine Nutrition During Pregnancy and Lactation on Child Cognitive Outcomes: A Review.Nutrients · 2025Review
- Iodine nutritional status in different trimesters of pregnancy and its association with dietary habits: a prospective observational study in Taiwan.BMC pregnancy and childbirth · 2025Observational
- Inadequate iodine status among women of childbearing age in Northern Norway: a cross-sectional study.Food & nutrition research · 2025Article
- Maternal iodine levels and associations with offspring outcomes and growth: a prospective birth cohort study of Chinese pregnant women.Frontiers in endocrinology · 2025Article
- Autoimmune Thyroid Disease and Pregnancy: The Interaction Between Genetics, Epigenetics and Environmental Factors.Journal of clinical medicine · 2024Review
- Adult dietary patterns and their association with iodine nutrition levels and thyroid function: a cross-sectional study.Public health nutrition · 2024Article
- Pregnant women at risk for iodine deficiency but adequate iodine intake in school-aged children of Zhejiang Province, China.Environmental geochemistry and health · 2024Article
- Nutritional Knowledge about Maternal and Newborn Health among Physiotherapists during the COVID-19 Pandemic in Minas Gerais, Brazil.Nutrients · 2024Article
- Maternal Urinary Iodine Concentration during Pregnancy and Its Impact on Child Growth and Neurodevelopment: An 11-Year Follow-Up Study.Nutrients · 2023Article
- Investigation of the effects of heat and light on iodine content of packaged and open salt brands collected from Jimma town.Heliyon · 2023Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Iodine is a necessary micronutrient for the production of thyroid hormones and normal human development. Despite the significant worldwide strategies for the prevention and control of iodine deficiency, it is still a prevalent public health issue, especially in pregnant women. Severe iodine deficiency during pregnancy and neonatal period is associated with many major and irreversible adverse effects, including an increased risk of pregnancy loss and infant mortality, neonatal hypothyroidism, cretinism, and neuropsychomotor retardation. We will review the impact of severe iodine deficiency on maternofetal, neonatal, and offspring outcomes. We will also discuss its epidemiology, classification of iodine deficiency severity, and current recommendations to prevent iodine deficiency in childbearing age and pregnant women.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.