Evidence map›Paper›PMID 32636712›Full record

ArticleTurkish journal of pharmaceutical sciences2020

Global DNA Hypomethylation and

Pınar TuzcuoĞlu, Sibel Özden

Open access · diamondAbstract read
In one paragraph

Article in Turkish journal of pharmaceutical sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Pınar TuzcuoĞluİstanbul University Faculty of Pharmacy, Department of Pharmaceutical Toxicology, İstanbul, Turkey.ORCID https://orcid.org/0000-0001-6533-4050
Sibel Özdenİstanbul University Faculty of Pharmacy, Department of Pharmaceutical Toxicology, İstanbul, Turkey.ORCID https://orcid.org/0000-0002-1662-2504
Istanbul University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesBisphenol A (BPA) is a synthetic monomer used in the production of polycarbonate and an environmental contaminant with endocrine disrupting properties. BPA release from plastic carriers is thought to cause high amounts of exposure, which result in high risk to human and environment health. MATERIALS AND

methodsThe study examined the possible changes in global DNA methylation, CpG promoter DNA methylation, and gene expressions of

resultsThe IC

conclusionThese results indicate that changes in global and gene-specific DNA methylation may play an important role in the mechanism of BPA toxicity in kidney cells.

Indexed as

Bisphenol Ac-mycDNA methylationNRK-52E cellsRassf1a

Identifiers

PMID32636712
PMCPMC7336029
OpenAlexW2982749782

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.