Evidence map›Paper›PMID 32636709›Full record

ArticleTurkish journal of pharmaceutical sciences2020

Mapping the Impact of a Polar Aprotic Solvent on the Microstructure and Dynamic Phase Transition in Glycerol Monooleate/Oleic Acid Systems.

Marzuka Shoeb Kazi, Mohammed Hassan Dehghan

Open access · diamondAbstract read
In one paragraph

Article in Turkish journal of pharmaceutical sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Marzuka Shoeb KaziY.B. Chavan College of Pharmacy, Department of Pharmaceutics, Dr. Rafiq Zakaria Campus, Aurangabad, India.ORCID https://orcid.org/0000-0002-6103-7806
Mohammed Hassan DehghanY.B. Chavan College of Pharmacy, Department of Pharmaceutics, Dr. Rafiq Zakaria Campus, Aurangabad, India.ORCID https://orcid.org/0000-0002-8082-9454
Government Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe impact of incorporating a polar aprotic solvent, dimethyl sulfoxide (DMSO), in glycerol monooleate/oleic acid systems was evaluated briefly to map its influence on the gel microstructure and dynamic phase transition in controlling the performance of a polyene antifungal drug delivery system. MATERIALS AND

methodsAn

resultsThe SAXS study identifies the coexistence of Im3m cubic phase with HCP P63/mmc hexagonal structures. The SAXS and DSC data highlight DMSO's unique ability to work both as a kosmotropic or chaotropic solvent and to be a function of its concentration. The

conclusionFinally, the antifungal IGFPS formulated was found to have the required low viscosity, responsive sol-gel phase transition, appreciative mechanical properties, and desirable antifungal effect with sustained drug release performance.

Indexed as

Dimethyl sulfoxideglycerol monooleatemicrostructureoleic acidsmall angle X-ray scattering

Identifiers

PMID32636709
PMCPMC7336036
OpenAlexW2966736536

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.