ArticleJournal of blood medicine2020
Proportion of Acute Transfusion Reaction and Associated Factors Among Adult Transfused Patients at Felege Hiwot Compressive Referral Hospital, Bahir Dar, Northwest Ethiopia: A Cross-Sectional Study.
Article in Journal of blood medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 15 citations in OpenAlex.
- Frequency of Acute Adverse Transfusion Reactions at King Saud Medical City, Riyadh, Saudi Arabia.Journal of clinical medicine · 2026Article
- Adverse Reactions to Blood Transfusion in Pediatric Cardiac Surgery: A Retrospective Cohort Study at a Single Center.Annals of cardiac anaesthesia · 2026Article
- A comprehensive analysis of transfusion trends and patient outcomes in blood utilization practices at Jimma university medical center.Scientific reports · 2025Article
- Development of Glutathione Hydrogel Carriers Containing Zinc Oxide Microparticles for Skin Regeneration Processes.International journal of molecular sciences · 2025Article
- A clinical audit of red blood cell transfusion practices at a district hospital in South Africa.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2024Article
- Blood Transfusion Complications and Associated Factors Among Blood-Transfused Adult Patients at Debre Markos Comprehensive Specialized Hospital, Ethiopia: A Cross Sectional Study.Journal of blood medicine · 2023Article
- Randomized double-blinded clinical trial on acute transfusion reactions in dogs receiving leukoreduced versus nonleukoreduced packed red blood cells.Journal of veterinary internal medicine · 2021Article
- Comparison of post-decompressive haematuria in rapid versus gradual bladder decompression in patients with chronic urinary retention.Journal of the West African College of SurgeonsReview
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAcute transfusion reactions are adverse events occurring within 24 hrs of transfusion and cause simple-to-severe complications. They may vary with the blood component transfused and recipient factors. In Ethiopia, there is a limited evidence about the incidence and associated factors of transfusion reactions.
objectiveTo determine the proportion of acute transfusion reactions and associated factors among adult transfused patients.
methodsA total of 384 study participants were included in the study. Structured questionnaires were used for socio-demographic and past medical history data collection. Vital signs were measured as a baseline for every study participants and monitored and followed for 24 hrs. Laboratory tests like complete blood count, direct anti-human globulin test and urine hemoglobin were done as a baseline for suspected patients. Cross-match, blood grouping, and blood culture for patients and donors sample were also done for suspected patients. Descriptive statistics, bivariable and multivariable binary logistic regression were analyzed using SPSS version 20. P-value of <0.05 in the multivariable model was considered as statistically significant.
resultsAcute transfusion reactions were observed in 5.2% of patients. Of total cases of acute transfusion reaction, the majority developed allergic reactions (65%) and febrile non-hemolytic transfusion reaction (30%). It was significantly associated with transfusion history (AOR=3.4; 95% CI: 1.2-9.7), abortion history (AOR=5.0; 95% CI: 1.5-16.4), longer blood storage time (AOR=5.1; 95% CI: 1.7-15.2) and receiving three or more unit of blood (AOR= 4.1; 95% CI: 1.5-11.2).
conclusionAcute transfusion reactions were observed in 5.2% of patients (allergic reactions (65%), febrile non-hemolytic transfusion reaction (30%) and alloimmunization (5%)). Patients with a history of transfusion, abortion, transfused with blood stored ≥14 days and multi-transfused patients should be closely monitored.
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