ReviewClinical ophthalmology (Auckland, N.Z.)2020
XEN
Review in Clinical ophthalmology (Auckland, N.Z.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 3 syntheses or guidelines pooled it, 88 citations in OpenAlex.
- Bleb characteristics following minimally invasive bleb surgeries in relation to surgical success using the anterior segment optical coherence tomography - a systematic review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Pooled it
- Minimally Invasive Bleb Surgery for Glaucoma: A Health Technology Assessment.Ontario health technology assessment series · 2024Pooled it
- Device-modified trabeculectomy for glaucoma.The Cochrane database of systematic reviews · 2023Pooled it
- Longitudinal OCT changes of the peripapillary RNFL after different glaucoma interventions - a comparative study.BMC ophthalmology · 2026Article
- Update on XEN Gel Stent: A Narrative Review on Indications, Surgical Technique, and Postoperative Management.Ophthalmology and therapy · 2026Review
- The Efficacy and Safety of Minimally Invasive Glaucoma Surgery for Primary Open-Angle Glaucoma: A Systematic Review.Healthcare (Basel, Switzerland) · 2026Review
- Management of Mixed Mechanism Glaucoma Secondary to NewColorIris Implant Using an Ab Externo Xen Gel Stent.Case reports in ophthalmological medicine · 2026Article
- XEN‑45 implantation for refractory secondary glaucoma.BMC ophthalmology · 2025Article
- Review
- Management of fracture and displacement of a previously successful bilateral transconjunctival ab-externo XEN gel stent: a case report.BMC ophthalmology · 2025Article
- Review
- Hydrogels in the clinic: An update.Bioengineering & translational medicine · 2024Review
- Complications Following XEN45 Gel Stent and Glaucoma Drainage Device Implantation During Glaucoma Fellowship.Cureus · 2024Article
- Double implantation of Xen 45 gel stent in primary open-angle glaucoma: a pilot study.International ophthalmology · 2024Article
- Swiss Multicenter Ab Interno XEN45 Gel Stent Study: 2-Year Real-World Data.Ophthalmology and therapy · 2024Article
- Clinical Results of the MINIject Implant for Suprachoroidal Drainage.Journal of clinical medicine · 2024Article
- Complications of XEN gel stent implantation for the treatment of glaucoma: a systematic review.Frontiers in medicine · 2024Review
- Effectiveness and safety of XEN45 implant over 12 months of follow-up: data from the XEN-Glaucoma Treatment Registry.Eye (London, England) · 2024Observational
- Bleb Morphology on Anterior-Segment Optical Coherence Tomography after XEN Gel Stent Implantation.Journal of clinical medicine · 2023Article
- Ab-externo canaloplasty with and without suture in highly myopic eyes.International ophthalmology · 2023Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The XEN Gel Microstent is a subconjunctival microinvasive glaucoma surgical device developed with the aim of improving the predictability and safety profile of bleb-forming glaucoma surgical procedures. The stent is a hydrophilic tube composed of a porcine gel cross-linked with glutaraldehyde with good stability and biocompatibility with minimal tissue reaction. This device has demonstrated promising outcomes with fewer risks compared to traditional surgeries. The aim of the review is to present early studies on different designs of the XEN Gel Stent, to summarize different surgical techniques of implantation and to analyze more comprehensively the results, complications and rates of needling of the commercially available device (Xen 45). The review will address separately special cases (PXG, UVG, ICE, congenital glaucoma) and describe small series and case reports.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.