Evidence map›Paper›PMID 32636339›Full record

ArticlePlant physiology2020

The Intrinsically Disordered Protein CARP9 Bridges HYL1 to AGO1 in the Nucleus to Promote MicroRNA Activity.

Ariel H Tomassi, Delfina A Re, Facundo Romani, Damian A Cambiagno, Lucía Gonzalo, Javier E Moreno, Agustin L Arce, Pablo A Manavella

Open access · bronzeAbstract read
In one paragraph

Article in Plant physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
6.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Plant microRNA maturation and function.Nature reviews. Molecular cell biology · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. The PpPep2-Triggered PTI-like Response in Peach Trees Is Mediated by miRNAs.International journal of molecular sciences · 2024
    Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Beyond Loading: Functions of Plant ARGONAUTE Proteins.International journal of molecular sciences · 2023
    Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Intrinsically disordered proteins SAID1/2 condensate on SERRATE for dual inhibition of miRNA biogenesis in Arabidopsis.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ariel H TomassiInstituto de Agrobiotecnología del Litoral, Consejo Nacional de Investigaciones Científicas y Técnicas, Universidad Nacional del Litoral, Facultad de Bioquímica y Ciencias Biológicas, 3000 Santa Fe, Argentina.ORCID 0000-0001-7523-1776
Delfina A ReInstituto de Agrobiotecnología del Litoral, Consejo Nacional de Investigaciones Científicas y Técnicas, Universidad Nacional del Litoral, Facultad de Bioquímica y Ciencias Biológicas, 3000 Santa Fe, Argentina.
Facundo RomaniInstituto de Agrobiotecnología del Litoral, Consejo Nacional de Investigaciones Científicas y Técnicas, Universidad Nacional del Litoral, Facultad de Bioquímica y Ciencias Biológicas, 3000 Santa Fe, Argentina.ORCID 0000-0003-3954-6740
Damian A CambiagnoInstituto de Agrobiotecnología del Litoral, Consejo Nacional de Investigaciones Científicas y Técnicas, Universidad Nacional del Litoral, Facultad de Bioquímica y Ciencias Biológicas, 3000 Santa Fe, Argentina.ORCID 0000-0001-9664-5900
Lucía GonzaloInstituto de Agrobiotecnología del Litoral, Consejo Nacional de Investigaciones Científicas y Técnicas, Universidad Nacional del Litoral, Facultad de Bioquímica y Ciencias Biológicas, 3000 Santa Fe, Argentina.
Javier E MorenoInstituto de Agrobiotecnología del Litoral, Consejo Nacional de Investigaciones Científicas y Técnicas, Universidad Nacional del Litoral, Facultad de Bioquímica y Ciencias Biológicas, 3000 Santa Fe, Argentina.ORCID 0000-0001-9763-5325
Agustin L ArceInstituto de Agrobiotecnología del Litoral, Consejo Nacional de Investigaciones Científicas y Técnicas, Universidad Nacional del Litoral, Facultad de Bioquímica y Ciencias Biológicas, 3000 Santa Fe, Argentina.ORCID 0000-0003-3619-3898
Pablo A ManavellaInstituto de Agrobiotecnología del Litoral, Consejo Nacional de Investigaciones Científicas y Técnicas, Universidad Nacional del Litoral, Facultad de Bioquímica y Ciencias Biológicas, 3000 Santa Fe, Argentina pablomanavella@ial.santafe-conicet.gov.ar.ORCID 0000-0003-3589-4414
Consejo Nacional de Investigaciones Científicas y Técnicas · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In plants, small RNAs are loaded into ARGONAUTE (AGO) proteins to fulfill their regulatory functions. MicroRNAs (miRNAs), one of the most abundant classes of endogenous small RNAs, are preferentially loaded into AGO1. Such loading, long believed to happen exclusively in the cytoplasm, was recently proposed to also occur in the nucleus. Here, we identified CONSTITUTIVE ALTERATIONS IN THE SMALL RNAS PATHWAYS9 (CARP9), a nuclear-localized, intrinsically disordered protein, as a factor promoting miRNA activity in Arabidopsis (

Indexed as

ArabidopsisArabidopsis ProteinsArgonaute ProteinsCell NucleusGene Expression Regulation, PlantIntrinsically Disordered ProteinsRNA-Binding ProteinsAGO1 protein, ArabidopsisArabidopsis ProteinsArgonaute ProteinsHYL1 protein, ArabidopsisIntrinsically Disordered ProteinsRNA-Binding Proteins

Identifiers

PMID32636339
PMCPMC7479909
OpenAlexW3041212913

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.