Evidence map›Paper›PMID 32636334›Full record

ArticlemSystems2020

Host and Parasite Transcriptomic Changes upon Successive Plasmodium falciparum Infections in Early Childhood.

Katie R Bradwell, Drissa Coulibaly, Abdoulaye K Koné, Matthew B Laurens, Ahmadou Dembélé, Youssouf Tolo, Karim Traoré, Amadou Niangaly, Andrea A Berry, Bourema Kouriba and 7 more

Open access · goldAbstract read
In one paragraph

Article in mSystems, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. RNAseq of Infected Erythrocyte Surface Antigen-Encoding Genes.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 2 countries.

Katie R BradwellInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA.ORCID https://orcid.org/0000-0002-9730-1808
Drissa CoulibalyMalaria Research and Training Center, University of Science, Techniques and Technologies, Bamako, Mali.
Abdoulaye K KonéMalaria Research and Training Center, University of Science, Techniques and Technologies, Bamako, Mali.
Matthew B LaurensMalaria Research Program, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.ORCID https://orcid.org/0000-0003-3874-581X
Ahmadou DembéléMalaria Research and Training Center, University of Science, Techniques and Technologies, Bamako, Mali.
Youssouf ToloMalaria Research and Training Center, University of Science, Techniques and Technologies, Bamako, Mali.
Karim TraoréMalaria Research and Training Center, University of Science, Techniques and Technologies, Bamako, Mali.
Amadou NiangalyMalaria Research and Training Center, University of Science, Techniques and Technologies, Bamako, Mali.
Andrea A BerryMalaria Research Program, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Bourema KouribaMalaria Research and Training Center, University of Science, Techniques and Technologies, Bamako, Mali.
Christopher V PloweDuke Global Health Institute, Duke University, Durham, North Carolina, USA.
Ogobara K DoumboMalaria Research and Training Center, University of Science, Techniques and Technologies, Bamako, Mali.
Kirsten E LykeMalaria Research Program, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Shannon Takala-HarrisonMalaria Research Program, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Mahamadou A TheraMalaria Research and Training Center, University of Science, Techniques and Technologies, Bamako, Mali.
Mark A TravassosMalaria Research Program, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA mtravass@som.umaryland.edu dserre@som.umaryland.edu.ORCID https://orcid.org/0000-0002-6045-3322
David SerreInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA mtravass@som.umaryland.edu dserre@som.umaryland.edu.
Université des Sciences, des Techniques et des Technologies de Bamako · MLUniversity of Maryland, Baltimore · USDuke University · US

Funding

Genetic diversity and protective immunity to malaria infection and diseaseU01AI065683 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI PLOWE, CHRISTOPHER V. · 2010 to 2014
$3.0M
MALARIA RESEARCH TRAINING IN MALID43TW001589 · FIC · UNIVERSITY OF MARYLAND BALTIMORE · PI PLOWE, CHRISTOPHER V. · 2000 to 2015
$2.8M
Variant surface antigens in cerebral malaria pathogenesisR01HL130750 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI FISHER, STEVEN A., PLOWE, CHRISTOPHER V. · 2015 to 2018
$2.1M
Malaria variant surface antigen expression and vulnerability to disease in Malian children with Hemoglobin C traitR01HL146377 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI TRAVASSOS, MARK A · 2019 to 2023
$1.9M
Host vulnerability and parasite genetics in the development of cerebral malariaR01AI099628 · NIAID · UNIV OF SCIENCES, TECH & TECH OF BAMAKO · PI THERA, MAHAMADOU ALI · 2014 to 2018
$625k
Host and Parasite Transcriptional Changes Associated with Immunity to Clinical Malaria in Malian ChildrenR21AI146853 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI SERRE, DAVID, TRAVASSOS, MARK A · 2019 to 2020
$425k
FIC NIH HHS D43 TW001589NHLBI NIH HHS R01 HL130750NHLBI NIH HHS R01 HL146377NIAID NIH HHS R01 AI099628NIAID NIH HHS R21 AI146853NIAID NIH HHS U01 AI065683
6 · The paper itself

Abstract

Children are highly susceptible to clinical malaria, and in regions where malaria is endemic, their immune systems must face successive encounters with

Indexed as

malariatranscriptomics

Identifiers

PMID32636334
PMCPMC7343306
OpenAlexW3038821011

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.