Evidence map›Paper›PMID 32636313›Full record

SynthesisBMJ global health2020

Estimating the yield of tuberculosis from key populations to inform targeted interventions in South Africa: a scoping review.

Lucy Andere Chimoyi, Christian Lienhardt, Nishila Moodley, Priya Shete, Gavin J Churchyard, Salome Charalambous

Open access · goldAbstract readMeta-AnalysisScoping Review
In one paragraph

Synthesis in BMJ global health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.1field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Experiences of key populations in multidrug-resistant TB and HIV.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2025
    Article
  2. Inferring bivariate associations with continuous data from studies using respondent-driven sampling.Journal of the Royal Statistical Society. Series C, Applied statistics · 2025
    Article
  3. Article
  4. Serial Mass Screening for Tuberculosis Among Incarcerated Persons in Brazil.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Lucy Andere ChimoyiThe Aurum Institute, Johannesburg, South Africa lchimoyi@auruminstitute.org.ORCID 0000-0002-0083-8319
Christian LienhardtGlobal Tuberculosis Program, World Health Organisation, Geneva, Switzerland.
Nishila MoodleyThe Aurum Institute, Johannesburg, South Africa.
Priya SheteGlobal Tuberculosis Program, World Health Organisation, Geneva, Switzerland.
Gavin J ChurchyardThe Aurum Institute, Johannesburg, South Africa.
Salome CharalambousThe Aurum Institute, Johannesburg, South Africa.
Aurum Institute · ZAWorld Health Organization · CHLondon School of Hygiene & Tropical Medicine · GBUniversity of the Witwatersrand · ZA

Funding

World Health Organization 001
6 · The paper itself

Abstract

introductionTuberculosis (TB) case finding strategies are recommended to increase yield for TB in key populations. Several key populations are identified in the literature, but techniques for estimating yield and prioritising interventions are needed.

methodsWe conducted a scoping review of existing evidence on TB burden to assess contribution of key populations to the TB epidemic in South Africa. Reports, articles and conference abstracts from January 2000 to December 2016 were reviewed to determine TB incidence, prevalence and size of key populations in South Africa. Meta-analysis summarised prevalence and incidence rates of TB in selected key populations assessed for heterogeneity. TB risk was calculated for each key population. Number needed to screen (NNS) to diagnose one case of TB disease was computed. Population attributable fraction estimated the potential impact of interventions on TB cases per population.

resultsThe search yielded 140 citations, of which 49 were included in the review and a final 32 were included in the meta-analysis. A high prevalence of TB disease was observed in HIV-infected patients with an estimated effect size (ES=0.25, 95% CI 0.20 to 0.30). Heterogeneity was high in this population (

conclusionsOur findings illustrate the of value using available epidemiological evidence to inform targeted TB interventions. This review suggests that targeting interventions towards inmates, PLHIV and informal settlements would have a bigger impact on TB burden in South Africa.

Indexed as

TuberculosisDelivery of Health CareHumansIncidencePrevalenceSouth Africaepidemiologyreviewtuberculosis

Identifiers

PMID32636313
PMCPMC7342464
OpenAlexW3040259706

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.