Evidence map›Paper›PMID 32636310›Full record

ArticleRNA (New York, N.Y.)2020

Validation strategies for antibodies targeting modified ribonucleotides.

Franziska Weichmann, Robert Hett, Aloys Schepers, Taku Ito-Kureha, Andrew Flatley, Kaouthar Slama, Florian D Hastert, Nicholas B Angstman, M Cristina Cardoso, Julian König and 7 more

Open access · bronzeAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

  1. The Secret Life of NJournal of molecular biology · 2025
    Review
  2. Article
  3. Review
  4. Differentiation and Growth-Arrest-Related lncRNA (International journal of molecular sciences · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. No evidence for epitranscriptomic mRNA (New York, N.Y.) · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 9 institutions in 1 country.

Franziska WeichmannRegensburg Center for Biochemistry, Laboratory for RNA Biology, University of Regensburg, 93053 Regensburg, Germany.
Robert HettRegensburg Center for Biochemistry, Laboratory for RNA Biology, University of Regensburg, 93053 Regensburg, Germany.
Aloys SchepersInstitute for Diabetes and Obesity, Monoclonal Antibody Core Facility and Research Group, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), 85764 Neuherberg, Germany.
Taku Ito-KurehaInstitute for Immunology, Biomedical Center of the Ludwig-Maximilians-University München, 82152 Planegg-Martinsried, Germany.
Andrew FlatleyInstitute for Diabetes and Obesity, Monoclonal Antibody Core Facility and Research Group, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), 85764 Neuherberg, Germany.
Kaouthar SlamaInstitute of Pharmacy and Biochemistry, Johannes-Gutenberg-Universität Mainz, 55128 Mainz, Germany.
Florian D HastertCell Biology and Epigenetics, Technische Universität Darmstadt, 64287 Darmstadt, Germany.
Nicholas B AngstmanGene Center, Ludwig-Maximilians-University Munich, 81377 Munich, Germany.
M Cristina CardosoCell Biology and Epigenetics, Technische Universität Darmstadt, 64287 Darmstadt, Germany.
Julian KönigInstitute of Molecular Biology (IMB), Ackermannweg 4, 55128 Mainz, Germany.
Stefan HüttelmaierInstitute of Molecular Medicine, Section for Molecular Cell Biology, Faculty of Medicine, Martin Luther University Halle-Wittenberg, Charles Tanford Protein Centre, 06120 Halle, Germany.
Christoph DieterichBioinformatics and Systems Cardiology, Klaus Tschira Institute for Integrative Computational Cardiology and Department of Internal Medicine III, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Stefan CanzarGene Center, Ludwig-Maximilians-University Munich, 81377 Munich, Germany.
Mark HelmInstitute of Pharmacy and Biochemistry, Johannes-Gutenberg-Universität Mainz, 55128 Mainz, Germany.
Vigo HeissmeyerInstitute for Immunology, Biomedical Center of the Ludwig-Maximilians-University München, 82152 Planegg-Martinsried, Germany.
Regina FeederleInstitute for Diabetes and Obesity, Monoclonal Antibody Core Facility and Research Group, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), 85764 Neuherberg, Germany.
Gunter MeisterRegensburg Center for Biochemistry, Laboratory for RNA Biology, University of Regensburg, 93053 Regensburg, Germany.
Helmholtz Zentrum München · DEUniversity of Regensburg · DEJohannes Gutenberg University Mainz · DELudwig-Maximilians-Universität München · DETechnische Universität Darmstadt · DEBernstein Center for Computational Neuroscience Munich · DEHeidelberg University · DEInstitute of Molecular Biology · DEMartin Luther University Halle-Wittenberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemical modifications are found on almost all RNAs and affect their coding and noncoding functions. The identification of m

Indexed as

AntibodiesNucleotidesRibonucleotidesRNARNA, MessengerAntibodiesNucleotidesRibonucleotidesRNARNA, Messengeraffinitybase modificationsm5Cm6Amonoclonal antibodiesvalidation

Identifiers

PMID32636310
PMCPMC7491328
OpenAlexW3041147533

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.