Evidence map›Paper›PMID 32636304›Full record

ArticleThe Journal of biological chemistry2020

The barley lectin, horcolin, binds high-mannose glycans in a multivalent fashion, enabling high-affinity, specific inhibition of cellular HIV infection.

Nisha Grandhi Jayaprakash, Amrita Singh, Rahul Vivek, Shivender Yadav, Sanmoy Pathak, Jay Trivedi, Narayanaswamy Jayaraman, Dipankar Nandi, Debashis Mitra, Avadhesha Surolia

Erratum issuedOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
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  5. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Nisha Grandhi JayaprakashMolecular Biophysics Unit, Indian Institute of Science, Bangalore, India.
Amrita SinghMolecular Biophysics Unit, Indian Institute of Science, Bangalore, India.
Rahul VivekMolecular Biophysics Unit, Indian Institute of Science, Bangalore, India.
Shivender YadavDepartment of Organic Chemistry, Indian Institute of Science, Bangalore, India.
Sanmoy PathakDepartment of Biochemistry, Indian Institute of Science, Bangalore, India.
Jay TrivediNational Centre for Cell Science, Pune University, Pune, India.
Narayanaswamy JayaramanDepartment of Organic Chemistry, Indian Institute of Science, Bangalore, India.
Dipankar NandiDepartment of Biochemistry, Indian Institute of Science, Bangalore, India.
Debashis MitraNational Centre for Cell Science, Pune University, Pune, India.
Avadhesha SuroliaMolecular Biophysics Unit, Indian Institute of Science, Bangalore, India. Electronic address: surolia@iisc.ac.in.
Indian Institute of Science Bangalore · INNational Centre for Cell Science · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HIV InfectionsAnimalsenv Gene Products, Human Immunodeficiency VirusHEK293 CellsHIV-1HIV Envelope Protein gp120HordeumHumansMaleMannoseMicePlant LectinsPolysaccharidesRabbitsenv Gene Products, Human Immunodeficiency Virusgp140 envelope protein, Human immunodeficiency virus 1HIV Envelope Protein gp120MannosePlant LectinsPolysaccharidesanti-HIV agentantiviral agentglycoproteinHIV gp120horcolinisothermal titration calorimetry (ITC)lectinmolecular dynamics

Identifiers

PMID32636304
PMCPMC7443486
OpenAlexW3041761530

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.