Evidence map›Paper›PMID 32636299›Full record

GuidelineThe European respiratory journal2020

Treatment of nontuberculous mycobacterial pulmonary disease: an official ATS/ERS/ESCMID/IDSA clinical practice guideline.

Charles L Daley, Jonathan M Iaccarino, Christoph Lange, Emmanuelle Cambau, Richard J Wallace, Claire Andrejak, Erik C Böttger, Jan Brozek, David E Griffith, Lorenzo Guglielmetti and 11 more

3 registry-linked trialsOpen access · bronzeAbstract readPractice Guideline
In one paragraph

Guideline in The European respiratory journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 537 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
537citing papers in PubMed, 3 pooled it
52.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05824988 recruitingnot on this mapstarted 2023, after this paper: background citation

Drug Exposure and Minimum Inhibitory Concentration in the Treatment of Mycobacterium Avium Complex Lung Disease: a Prospective Observational Cohort Study

TypeobservationalSponsorShanghai Pulmonary Hospital, Shanghai, ChinaRan2023 to 2026Enrolled100ConditionsMycobacterium Avium Complex, Mycobacterium Avium-Intracellulare Infection, Gram-Positive Bacterial Infections, Mycobacterium InfectionsArmsDrug exposure
NCT05861258 phase2terminatednot on this mapstarted 2023, after this paper: background citation

Pharmacokinetic Study of Minocycline in Patients With Pulmonary Nontuberculous Mycobacterial Disease

TypeinterventionalSponsorRadboud University Medical CenterRan2023 to 2025Enrolled12ConditionsMycobacterium Avium Complex Pulmonary DiseaseArmsMinocycline
NCT07363798 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Association of Nutrition and T Cell Immune Activity With Disease Progression in Nontuberculous Mycobacterial Pulmonary Disease

Typeobservational_patient_registrySponsorSeoul National University HospitalRan2026 to 2027Enrolled50ConditionsNontuberculous Mycobacterial Pulmonary Disease, Nontuberculous Mycobacterial Lung Disease
3 · Its place in the literature

Who cites it

537 citing papers in PubMed, 3 syntheses or guidelines pooled it, 834 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. A systematic review of tetracyclines for nontuberculous mycobacteria: focus on rapidly growing mycobacteria.European respiratory review : an official journal of the European Respiratory Society · 2025
    Pooled it
  4. Trial
  5. Intermittent versus Daily Therapy for NoncavitaryAnnals of the American Thoracic Society · 2025
    Trial
  6. Treatment Outcomes ofOpen forum infectious diseases · 2025
    Trial
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Observational
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article

477 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 16 institutions in 9 countries.

Charles L DaleyDept of Medicine, National Jewish Health, Denver, CO, USA.
Jonathan M IaccarinoPulmonary Center, Boston University School of Medicine, Boston, MA, USA.
Christoph LangeDivision of Clinical Infectious Diseases, Research Center Borstel, Borstel, Germany.
Emmanuelle CambauNational Reference Center for Mycobacteria and Antimycobacterial Resistance, APHP -Hôpital Lariboisière, Bacteriology; Inserm, University Paris Diderot, IAME UMR1137, Paris, France.
Richard J WallaceMycobacteria/Nocardia Laboratory, Dept of Microbiology, The University of Texas Health Science Center, Tyler, TX, USA.
Claire AndrejakRespiratory and Intensive Care Unit, University Hospital Amiens, Amiens, France.
Erik C BöttgerInstitute of Medical Microbiology, National Reference Center for Mycobacteria, University of Zurich, Zurich, Switzerland.
Jan BrozekDept of Clinical Epidemiology and Biostatistics, McMaster University Health Sciences Centre, Hamilton, ON, Canada.ORCID 0000-0002-3122-0773
David E GriffithPulmonary Infectious Disease Section, University of Texas Health Science Center, Tyler, TX, USA.
Lorenzo GuglielmettiNational Reference Center for Mycobacteria and Antimycobacterial Resistance, APHP -Hôpital Lariboisière, Bacteriology; Inserm, University Paris Diderot, IAME UMR1137, Paris, France.ORCID 0000-0003-0886-9635
Gwen A HuittDept of Medicine, National Jewish Health, Denver, CO, USA.ORCID 0000-0003-0398-8109
Shandra L KnightLibrary and Knowledge Services, National Jewish Health, Denver, CO, USA.
Philip LeitmanNTM Info and Research, Miami, FL, USA.
Theodore K MarrasDept of Medicine, University of Toronto and University Health Network, Toronto, ON, Canada.
Kenneth N OlivierPulmonary Branch, National Heart, Lung and Blood Institute, Bethesda, MD, USA.ORCID 0000-0001-8200-255X
Miguel SantinService of Infectious Diseases, Bellvitge University Hospital-IDIBELL, University of Barcelona, L'Hospitalet de Llobregat, Barcelona, Spain.ORCID 0000-0002-8474-3543
Jason E StoutDivision of Infectious Diseases and International Health, Duke University Medical Center, Durham, NC, USA.ORCID 0000-0002-6698-8176
Enrico TortoliEmerging Bacterial Pathogens Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.ORCID 0000-0001-5512-704X
Jakko van IngenRadboud Center for Infectious Diseases, Dept of Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID 0000-0002-0581-2003
Dirk WagnerDivision of Infectious Diseases, Dept of Medicine II, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.ORCID 0000-0002-3271-5815
Kevin L WinthropDivisions of Infectious Diseases, Schools of Public Health and Medicine, Oregon Health and Science University, Portland, OR, USA.
National Jewish Health · USInserm · FRThe University of Texas Health Science Center at Tyler · USBellvitge University Hospital · ESBoston University · USCentre Hospitalier Universitaire Amiens-Picardie · FRDuke Medical Center · USKarolinska Institutet · SEMcMaster University Medical Centre · CANational Heart Lung and Blood Institute · USOregon Health & Science University · USRadboud University Nijmegen · NLUniversity Health Network · CAUniversity of Freiburg · DEUniversity of Zurich · CHVita-Salute San Raffaele University · IT

Funding

Bronchiectasis and chronic airway infectionZIAHL006200 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI FENNELLY, KEVIN · 2015 to 2025
$25.1M
Intramural NIH HHS Z99 HL999999Intramural NIH HHS ZIA HL006200
6 · The paper itself

Abstract

Nontuberculous mycobacteria (NTM) represent over 190 species and subspecies, some of which can produce disease in humans of all ages and can affect both pulmonary and extrapulmonary sites. This guideline focuses on pulmonary disease in adults (without cystic fibrosis or human immunodeficiency virus infection) caused by the most common NTM pathogens such as

Indexed as

Mycobacterium abscessusMycobacterium Infections, NontuberculousMycobacterium kansasiiAdultHumansMycobacterium avium ComplexNontuberculous Mycobacteria

Identifiers

PMID32636299
PMCPMC8375621
OpenAlexW3038927358

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.