Evidence map›Paper›PMID 32635985›Full record

ReviewBMB reports2020

Emerging functions for ANKHD1 in cancer-related signaling pathways and cellular processes.

Bruna Oliveira de Almeida, João Agostinho Machado-Neto

Open access · goldAbstract readReview
In one paragraph

Review in BMB reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Bruna Oliveira de AlmeidaDepartment of Pharmacology, Biomedical Sciences Institute, University of São Paulo, São Paulo 05508-000, Brazil.
João Agostinho Machado-NetoDepartment of Pharmacology, Biomedical Sciences Institute, University of São Paulo, São Paulo 05508-000, Brazil.
Universidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ANKHD1 (ankyrin repeat and KH domain containing 1) is a large protein characterized by the presence of multiple ankyrin repeats and a K-homology domain. Ankyrin repeat domains consist of widely existing protein motifs in nature, they mediate protein-protein interactions and regulate fundamental biological processes, while the KH domain binds to RNA or ssDNA and is associated with transcriptional and translational regulation. In recent years, studies containing relevant information on ANKHD1 in cancer biology and its clinical relevance, as well as the increasing complexity of signaling networks in which this protein acts, have been reported. Among the signaling pathways of interest in oncology regulated by ANKHD1 are Hippo signaling, JAK/STAT, and STMN1. The scope of the present review is to survey the current knowledge and highlight future perspectives for ANKHD1 in the malignant phenotype of cancer cells, exploring biological, functional, and clinical reports of this protein in cancer. [BMB Reports 2020; 53(8): 413-418].

Indexed as

Adaptor Proteins, Signal TransducingAmino Acid MotifsBinding SitesBiological PhenomenaCell Line, TumorCell ProliferationGene Expression Regulation, NeoplasticHumansJanus Kinase 1NeoplasmsProtein DomainsRNARNA-Binding ProteinsSignal TransductionStathminSTAT Transcription FactorsAdaptor Proteins, Signal TransducingANKHD1 protein, humanJanus Kinase 1RNARNA-Binding ProteinsStathminSTAT Transcription FactorsTranscription FactorsYAP1 protein, humanYAP-Signaling Proteins

Identifiers

PMID32635985
PMCPMC7473474
OpenAlexW3041398940

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.