Evidence map›Paper›PMID 32635926›Full record

ArticleBMC research notes2020

Prevalence of hepatitis C in the adult population of Bulgaria: a pilot study.

Ida Sperle, Stine Nielsen, Martyna Gassowski, Zlatina Naneva, Tanya Perchemlieva, Andrew Amato-Gauci, Matthias An der Heiden, Viviane Bremer, Elitsa Golkocheva-Markova, Kristiyan Hristov and 6 more

Open access · goldAbstract read
In one paragraph

Article in BMC research notes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. [Epidemiology of viral hepatitis A to E in Germany].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2022
    Review
  2. Observational
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 3 countries.

Ida SperleDepartment of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany. sperle-heupeli@rki.de.
Stine NielsenIndependent Consultant, Madrid, Spain.
Martyna GassowskiDepartment of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.
Zlatina NanevaRegional Health Inspectorate, Stara Zagora, Bulgaria.
Tanya PerchemlievaRegional Health Inspectorate, Stara Zagora, Bulgaria.
Andrew Amato-GauciEuropean Centre for Disease Prevention and Control, Stockholm, Sweden.
Matthias An der HeidenDepartment of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.
Viviane BremerDepartment of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.
Elitsa Golkocheva-MarkovaNational Reference Laboratory "Hepatitis Viruses", Department of Virology, National Center of Infectious and Parasitic Diseases, Sofia, Bulgaria.
Kristiyan HristovMinistry of Health, Sofia, Bulgaria.
Elena KanevaRegional Health Inspectorate, Stara Zagora, Bulgaria.
Yanita SimeonovaDepartment of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.
Tencho TenevNational Reference Laboratory "Hepatitis Viruses", Department of Virology, National Center of Infectious and Parasitic Diseases, Sofia, Bulgaria.
Tonka VarlevaMinistry of Health, Sofia, Bulgaria.
Erika DuffellEuropean Centre for Disease Prevention and Control, Stockholm, Sweden.
Ruth ZimmermannDepartment of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.
Robert Koch Institute · DEEuropean Centre for Disease Prevention and Control · SENational Center of Infectious and Parasitic Diseases · BGCharité - Universitätsmedizin Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study piloted a European technical protocol for conducting chronic hepatitis C prevalence surveys in the general population. The pilot study took place in the Bulgarian city of Stara Zagora in 2018, and results of setting up, conducting and evaluating the survey are presented.

resultsA probability-based sample of the general adult population was drawn from the local population registry, stratified by age and sex. A sample size of 999 was calculated, and accounting for 50% non-response, 1998 registered invitation letters were sent. Venous blood samples and questionnaire data were collected by the Regional Health Inspectorate in Stara Zagora. Blood samples were tested for anti-HCV, and if reactive for RNA. 252 (21.6%) of the participants were included in the study. Mean age and sex distribution differed between the participants (55.9 years, 60.3% females) and the total sample (48.9 years, 53.4%). The weighted chronic HCV prevalence among participants was 0.9% [95% CI 0.2-4.2%]. The approach of only sending registered letters contributed to a low response rate, and more efforts are needed to reduce non-response, especially among men and younger age groups. Results of the evaluation were integrated in the final technical protocol.

Indexed as

AdolescentAdultAgedAged, 80 and overBulgariaCross-Sectional StudiesFemaleHepatitis C, ChronicHumansMaleMiddle AgedPilot ProjectsPrevalenceYoung AdultBulgariaGeneral populationHCVHepatitis CPrevalencePrevalence survey

Identifiers

PMID32635926
PMCPMC7341663
OpenAlexW3038802802

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.