ArticleBMC psychiatry2020
Males are more sensitive to reward and less sensitive to loss than females among people with internet gaming disorder: fMRI evidence from a card-guessing task.
Article in BMC psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 45 citations in OpenAlex.
- Sex Difference in Brain Responses During Short Abstinence in People With Internet Gaming Disorder.Addiction biology · 2026Article
- Longitudinal Association Between Internet Gaming Disorder and School Refusal Among Adolescents Using a Random Intercept Cross-Lagged Panel Model: Three-Wave Prospective Cohort Study.JMIR serious games · 2026Article
- Atypical cortical neural activity in internet gaming disorder comorbid with autism spectrum disorder during a cue reactivity task: A magnetoencephalography study.PCN reports : psychiatry and clinical neurosciences · 2026Article
- Internet gaming disorder among individuals with autism spectrum disorder in the Kingdom of Saudi Arabia: a comparative study.Frontiers in public health · 2026Article
- Neuroimaging Evidence of Facial Emotion Processing in Autism Spectrum Disorder: A Meta-Analysis of Functional Neuroimaging Studies.Journal of autism and developmental disorders · 2025Article
- Validation and psychometric evaluation of the Turkish version of the Reward Deficiency Syndrome Questionnaire (RDSQ-29).Dusunen adam : Bakirkoy Ruh ve Sinir Hastaliklari Hastanesi yayin organi · 2025Article
- Sex-specific associations of episode type in bipolar I disorder with neuro-metabolic lateralization of the cortico-striatal-cerebellar (CSC) circuit.BMC psychiatry · 2025Article
- Neural responses to kills/deaths in real MOBA games are associated with addiction-related psychological traits and subjective pleasant/unpleasant experiences.Journal of behavioral addictions · 2025Article
- Mediating role of depression and gender in the relationship between daily video games exposure and internet gaming disorder (IGD) among college students.BMC psychology · 2025Article
- Increasingly dependent on habit? A study on the electrophysiological mechanisms of goal-directed and habitual control in internet gaming disorder.Journal of behavioral addictions · 2025Article
- Love at first glance: Imbalanced processing to gaming and natural rewards in internet gaming disorder.Journal of behavioral addictions · 2025Article
- Gender differences in problematic gaming among Chinese adolescents and young adults.BMC psychiatry · 2025Article
- Novel rat model of gaming disorder: assessment of social reward and sex differences in behavior and c-Fos brain activity.Psychopharmacology · 2025Article
- Prefrontal cortex responses to game rewards and losses in individuals with Internet Gaming Disorder: Insights from fNIRS during mobile gameplay.Journal of behavioral addictions · 2025Article
- A Functional Magnetic Resonance Imaging Investigation of Hot and Cool Executive Functions in Reward and Competition.Sensors (Basel, Switzerland) · 2025Article
- Reduced loss aversion in value-based decision-making and edge-centric functional connectivity in patients with internet gaming disorder.Journal of behavioral addictions · 2023Article
- Gender difference in network relationship between inter-temporal decisions and prefrontal activation levels in internet gaming disorder.Psychoradiology · 2023Article
- Characteristics of brain activation in high-level football players at different stages of decision-making tasks off the ball: an fMRI study.Frontiers in human neuroscience · 2023Article
- Structure-function coupling within the reward network in preschool children predicts executive functioning in later childhood.Developmental cognitive neuroscience · 2022Article
- Latent Profile of Internet and Internet Game Usage Among South Korean Adolescents During the COVID-19 Pandemic.Frontiers in psychiatry · 2021Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundMany studies have found an interesting issue in the Internet gaming disorder (IGD): males are always observed to be the majority. However, there are little research to exploring the differences in the neural mechanisms between males and females in decision-making process among people with IGD. Therefore, explore the reward/loss processing between different gender with IGD could help in understanding the underlying neural mechanism of IGD.
methodsData from functional magnetic resonance imaging (fMRI) were collected from 111 subjects (IGD: 29 males, 25 females; recreational internet game user (RGU): 36 males, 21 females) while they were performing a card-guessing task. We collected and compared their brain features when facing the win and loss conditions in different groups.
resultsFor winning conditions, IGD group showed hypoactivity in the lingual gyrus than RGU group, male players showed hyperactivity in the left caudate nucleus, bilateral cingulate gyrus, right middle frontal gyrus (MFG), right precuneus and inferior parietal lobule relative to the females. And significant sex-by-group interactions results showed higher brain activities in the thalamus, parahippocampal gyrus and lower brain activities in Inferior frontal gyrus (IFG) were observed in males with IGD than females. For losing conditions, IGD group showed hypoactivity in the left lingual gyrus, parahippocampal gyrus and right anterior cingulate cortex (ACC) compared to the RGU group, male players showed hyperactive left caudate nucleus and hypoactive right middle occipital gyrus relative to females. And significant sex-by-group interactions results showed that compared to females with IGD, males with IGD showed decreased brain activities in the IFG and lingual gyrus.
conclusionsFirst, there appeared to be no difference in reward processing between the IGD and RGU group, but IGD showed less sensitivity to loss. Secondly, male players showed more sensitivity to rewards and less sensitivity to losses. Last but not least, males and females showed opposite activation patterns in IGD degree and rewards/losses processing. And male IGD subjects are more sensitive to reward and less sensitive to loss than females, which might be the reason for the gender different rates on IGD.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.