Evidence map›Paper›PMID 32635899›Full record

ArticleBMC ophthalmology2020

Effect of silicone oil on peripapillary capillary density in patients with rhegmatogenous retinal detachment.

Erqian Wang, Youxin Chen, Ningning Li, Hanyi Min

Open access · goldAbstract read
In one paragraph

Article in BMC ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
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  3. Microstructural and hemodynamic changes in the fundus after pars plana vitrectomy for different vitreoretinal diseases.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Erqian WangDepartment of Ophthalmology, Peking Union Medical College Hospital, No.1 Shuai Fu Yuan, Dongcheng District, Beijing, 100730, China.
Youxin ChenDepartment of Ophthalmology, Peking Union Medical College Hospital, No.1 Shuai Fu Yuan, Dongcheng District, Beijing, 100730, China.
Ningning LiDepartment of Ophthalmology, Peking Union Medical College Hospital, No.1 Shuai Fu Yuan, Dongcheng District, Beijing, 100730, China.
Hanyi MinDepartment of Ophthalmology, Peking Union Medical College Hospital, No.1 Shuai Fu Yuan, Dongcheng District, Beijing, 100730, China. minhy@pumch.cn.ORCID http://orcid.org/0000-0002-5415-879X
Chinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

Non-Profit Central Research Institute Fund of Chinese Academy of Medical Sciences 2018PT32029
6 · The paper itself

Abstract

purposeTo evaluate the effect of silicone oil (SO) on peripapillary blood flow using OCT angiography.

methodsThis prospective case series recruited patients with unilateral rhegmatogenous retinal detachment (RRD) who underwent vitrectomy and SO tamponade. Patients were examined before SO removal and at 10 days, 1 month, and 3 months after SO removal on a spectral domain OCT angiography device (RTVue XR Avanti, Optovue Inc., CA, USA) for the measurement of radial peripapillary capillaries (RPC) vessel density (VD) in global field, superior hemifield, and inferior hemifield. Changes in RPC VD following SO removal were compared between affected eyes and contralateral eyes.

resultsTwenty-two patients were analyzed. The average duration of SO tamponade was 101.3 days (range, 90 to 119 days). After SO removal, global RPC VD increased by 1.3% (95%CI, 0.3 to 2.3%), compared with a - 0.4% (95%CI, - 1.4 to 0.7%) change in contralateral eyes (P = 0.007). The increase in RPC VD after SO removal mainly occurred in the superior hemifield, which was 1.6% (95%CI, 0.6 to 2.7%). The increase in RPC VD in the inferior hemifield was 1.0% (95%CI, - 0.2 to 2.1%) after SO removal.

conclusionsWe detected a mild increase in peripapillary capillary density after SO removal, mainly in the superior hemifield. Our results suggested that SO tamponade could have negative effect on peripapillary blood flow, possibly by capillary compression.

Indexed as

Retinal DetachmentSilicone OilsCapillariesHumansProspective StudiesRetinal VesselsTomography, Optical CoherenceSilicone OilsOptical coherence tomography angiographyOptic neuropathyRadial peripapillary capillariesRhegmatogenous retinal detachmentSilicone oil

Identifiers

PMID32635899
PMCPMC7339486
OpenAlexW3040632458

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.